Anti-F™/ RPGRIP1L/ CORS3 monoclonal antibody

Anti-F™/ RPGRIP1L/ CORS3 antibody for FACS & in-vivo assay

Target products collectionGo to RPGRIP1L/RPGRIP1L products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2308-Ab-1/ GM-Tg-hg-MP2308-Ab-2Anti-Human RPGRIP1L monoclonal antibodyHuman
GM-Tg-rg-MP2308-Ab-1/ GM-Tg-rg-MP2308-Ab-2Anti-Rat RPGRIP1L monoclonal antibodyRat
GM-Tg-mg-MP2308-Ab-1/ GM-Tg-mg-MP2308-Ab-2Anti-Mouse RPGRIP1L monoclonal antibodyMouse
GM-Tg-cynog-MP2308-Ab-1/ GM-Tg-cynog-MP2308-Ab-2Anti-Cynomolgus/ Rhesus macaque RPGRIP1L monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2308-Ab-1/ GM-Tg-felg-MP2308-Ab-2Anti-Feline RPGRIP1L monoclonal antibodyFeline
GM-Tg-cang-MP2308-Ab-1/ GM-Tg-cang-MP2308-Ab-2Anti-Canine RPGRIP1L monoclonal antibodyCanine
GM-Tg-bovg-MP2308-Ab-1/ GM-Tg-bovg-MP2308-Ab-2Anti-Bovine RPGRIP1L monoclonal antibodyBovine
GM-Tg-equg-MP2308-Ab-1/ GM-Tg-equg-MP2308-Ab-2Anti-Equine RPGRIP1L monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2308-Ab-1/ GM-Tg-hg-MP2308-Ab-2; GM-Tg-rg-MP2308-Ab-1/ GM-Tg-rg-MP2308-Ab-2;
GM-Tg-mg-MP2308-Ab-1/ GM-Tg-mg-MP2308-Ab-2; GM-Tg-cynog-MP2308-Ab-1/ GM-Tg-cynog-MP2308-Ab-2;
GM-Tg-felg-MP2308-Ab-1/ GM-Tg-felg-MP2308-Ab-2; GM-Tg-cang-MP2308-Ab-1/ GM-Tg-cang-MP2308-Ab-2;
GM-Tg-bovg-MP2308-Ab-1/ GM-Tg-bovg-MP2308-Ab-2; GM-Tg-equg-MP2308-Ab-1/ GM-Tg-equg-MP2308-Ab-2
Products NameAnti-RPGRIP1L monoclonal antibody
Formatmab
Target NameRPGRIP1L
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-RPGRIP1L benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species F™/ RPGRIP1L/ CORS3 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2308
    Target NameRPGRIP1L
    Gene ID23322,244585,307724,697345,487278,101099852,518659,100050527
    Gene Symbol and Synonyms1700047E16Rik,4931437C01,COACH3,CORS3,F™,JBTS7,MKS5,NPHP8,PPP1R134,RGD1311099,RPGRIP1L
    Uniprot AccessionQ68CZ1
    Uniprot Entry NameF™_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000103494
    Target ClassificationN/A

    The target: RPGRIP1L, gene name: RPGRIP1L, also named as CORS3, F™, JBTS7, MKS5, NPHP8, PPP1R134. The protein encoded by this gene can localize to the basal body-centrosome complex or to primary cilia and centrosomes in ciliated cells. The encoded protein has been found to interact with nephrocystin-4. Defects in this gene are a cause of Joubert syndrome type 7 (JBTS7) and Meckel syndrome type 5 (MKS5). [provided by RefSeq, Jun 2016].



    About Gmab

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    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.