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Anti-RL36A/ RPL36A/ L36A monoclonal antibody
Anti-RL36A/ RPL36A/ L36A antibody for FACS & in-vivo assay
Go to RPL36A/RPL36A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2309-Ab-1/ GM-Tg-hg-MP2309-Ab-2 | Anti-Human RPL36A monoclonal antibody | Human |
| GM-Tg-rg-MP2309-Ab-1/ GM-Tg-rg-MP2309-Ab-2 | Anti-Rat RPL36A monoclonal antibody | Rat |
| GM-Tg-mg-MP2309-Ab-1/ GM-Tg-mg-MP2309-Ab-2 | Anti-Mouse RPL36A monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2309-Ab-1/ GM-Tg-cynog-MP2309-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RPL36A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2309-Ab-1/ GM-Tg-felg-MP2309-Ab-2 | Anti-Feline RPL36A monoclonal antibody | Feline |
| GM-Tg-cang-MP2309-Ab-1/ GM-Tg-cang-MP2309-Ab-2 | Anti-Canine RPL36A monoclonal antibody | Canine |
| GM-Tg-bovg-MP2309-Ab-1/ GM-Tg-bovg-MP2309-Ab-2 | Anti-Bovine RPL36A monoclonal antibody | Bovine |
| GM-Tg-equg-MP2309-Ab-1/ GM-Tg-equg-MP2309-Ab-2 | Anti-Equine RPL36A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2309-Ab-1/ GM-Tg-hg-MP2309-Ab-2; GM-Tg-rg-MP2309-Ab-1/ GM-Tg-rg-MP2309-Ab-2; GM-Tg-mg-MP2309-Ab-1/ GM-Tg-mg-MP2309-Ab-2; GM-Tg-cynog-MP2309-Ab-1/ GM-Tg-cynog-MP2309-Ab-2; GM-Tg-felg-MP2309-Ab-1/ GM-Tg-felg-MP2309-Ab-2; GM-Tg-cang-MP2309-Ab-1/ GM-Tg-cang-MP2309-Ab-2; GM-Tg-bovg-MP2309-Ab-1/ GM-Tg-bovg-MP2309-Ab-2; GM-Tg-equg-MP2309-Ab-1/ GM-Tg-equg-MP2309-Ab-2 |
| Products Name | Anti-RPL36A monoclonal antibody |
| Format | mab |
| Target Name | RPL36A |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RPL36A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species RL36A/ RPL36A/ L36A VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2309 |
| Target Name | RPL36A |
| Gene ID | 6173,19982,292964,100060331 |
| Gene Symbol and Synonyms | eL42,L36A,L44L,MIG6,RPL36A,RPL44 |
| Uniprot Accession | P83881,P83883 |
| Uniprot Entry Name | RL36A_HUMAN,RL36A_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000241343 |
| Target Classification | N/A |
The target: RPL36A, gene name: RPL36A, also named as L36A, L44L, MIG6, RPL44. Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with yeast ribosomal protein L44, belongs to the L44E (L36AE) family of ribosomal proteins. Although this gene has been referred to as ribosomal protein L44 (RPL44), its official name is ribosomal protein L36a (RPL36A). This gene and the human gene officially named ribosomal protein L36a-like (RPL36AL) encode nearly identical proteins; however, they are distinct genes. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Naturally occurring read-through transcription occurs between this locus and the heterogeneous nuclear ribonucleoprotein H2 (H') gene. [provided by RefSeq, Jan 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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