Anti-RL36L/ RPL36AL/ RPL36A monoclonal antibody

Anti-RL36L/ RPL36AL/ RPL36A antibody for FACS & in-vivo assay

Target products collectionGo to RPL36AL/RPL36AL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2311-Ab-1/ GM-Tg-hg-MP2311-Ab-2Anti-Human RPL36AL monoclonal antibodyHuman
GM-Tg-rg-MP2311-Ab-1/ GM-Tg-rg-MP2311-Ab-2Anti-Rat RPL36AL monoclonal antibodyRat
GM-Tg-mg-MP2311-Ab-1/ GM-Tg-mg-MP2311-Ab-2Anti-Mouse RPL36AL monoclonal antibodyMouse
GM-Tg-cynog-MP2311-Ab-1/ GM-Tg-cynog-MP2311-Ab-2Anti-Cynomolgus/ Rhesus macaque RPL36AL monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2311-Ab-1/ GM-Tg-felg-MP2311-Ab-2Anti-Feline RPL36AL monoclonal antibodyFeline
GM-Tg-cang-MP2311-Ab-1/ GM-Tg-cang-MP2311-Ab-2Anti-Canine RPL36AL monoclonal antibodyCanine
GM-Tg-bovg-MP2311-Ab-1/ GM-Tg-bovg-MP2311-Ab-2Anti-Bovine RPL36AL monoclonal antibodyBovine
GM-Tg-equg-MP2311-Ab-1/ GM-Tg-equg-MP2311-Ab-2Anti-Equine RPL36AL monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2311-Ab-1/ GM-Tg-hg-MP2311-Ab-2; GM-Tg-rg-MP2311-Ab-1/ GM-Tg-rg-MP2311-Ab-2;
GM-Tg-mg-MP2311-Ab-1/ GM-Tg-mg-MP2311-Ab-2; GM-Tg-cynog-MP2311-Ab-1/ GM-Tg-cynog-MP2311-Ab-2;
GM-Tg-felg-MP2311-Ab-1/ GM-Tg-felg-MP2311-Ab-2; GM-Tg-cang-MP2311-Ab-1/ GM-Tg-cang-MP2311-Ab-2;
GM-Tg-bovg-MP2311-Ab-1/ GM-Tg-bovg-MP2311-Ab-2; GM-Tg-equg-MP2311-Ab-1/ GM-Tg-equg-MP2311-Ab-2
Products NameAnti-RPL36AL monoclonal antibody
Formatmab
Target NameRPL36AL
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-RPL36AL benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species RL36L/ RPL36AL/ RPL36A VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2311
    Target NameRPL36AL
    Gene ID6166,66483,81769,706548,480311,101091877,613592,100146851
    Gene Symbol and Synonyms2410038A03Rik,RPL36A,RPL36AL,Rpl36al1,RPL36AP42,RPL36A_18_1363,Rpl44
    Uniprot AccessionQ969Q0,P83883,D0VWQ4
    Uniprot Entry NameRL36L_HUMAN,RL36A_RAT,RL36A_CANLF
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000165502
    Target ClassificationN/A

    The target: RPL36AL, gene name: RPL36AL, also named as RPL36A. Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with yeast ribosomal protein L44, belongs to the L44E (L36AE) family of ribosomal proteins. This gene and the human gene officially named ribosomal protein L36a (RPL36A) encode nearly identical proteins; however, they are distinct genes. Although the name of this gene has been referred to as ribosomal protein L36a (RPL36A), its official name is ribosomal protein L36a-like (RPL36AL). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.