Anti-S10AD/ S100A13 monoclonal antibody
Anti-S10AD/ S100A13 antibody for FACS & in-vivo assay
Go to S100A13/S100A13 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-MP2314-Ab-1/ GM-Tg-hg-MP2314-Ab-2 | Anti-Human S100A13 monoclonal antibody | Human |
GM-Tg-rg-MP2314-Ab-1/ GM-Tg-rg-MP2314-Ab-2 | Anti-Rat S100A13 monoclonal antibody | Rat |
GM-Tg-mg-MP2314-Ab-1/ GM-Tg-mg-MP2314-Ab-2 | Anti-Mouse S100A13 monoclonal antibody | Mouse |
GM-Tg-cynog-MP2314-Ab-1/ GM-Tg-cynog-MP2314-Ab-2 | Anti-Cynomolgus/ Rhesus macaque S100A13 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-MP2314-Ab-1/ GM-Tg-felg-MP2314-Ab-2 | Anti-Feline S100A13 monoclonal antibody | Feline |
GM-Tg-cang-MP2314-Ab-1/ GM-Tg-cang-MP2314-Ab-2 | Anti-Canine S100A13 monoclonal antibody | Canine |
GM-Tg-bovg-MP2314-Ab-1/ GM-Tg-bovg-MP2314-Ab-2 | Anti-Bovine S100A13 monoclonal antibody | Bovine |
GM-Tg-equg-MP2314-Ab-1/ GM-Tg-equg-MP2314-Ab-2 | Anti-Equine S100A13 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-MP2314-Ab-1/ GM-Tg-hg-MP2314-Ab-2; GM-Tg-rg-MP2314-Ab-1/ GM-Tg-rg-MP2314-Ab-2; GM-Tg-mg-MP2314-Ab-1/ GM-Tg-mg-MP2314-Ab-2; GM-Tg-cynog-MP2314-Ab-1/ GM-Tg-cynog-MP2314-Ab-2; GM-Tg-felg-MP2314-Ab-1/ GM-Tg-felg-MP2314-Ab-2; GM-Tg-cang-MP2314-Ab-1/ GM-Tg-cang-MP2314-Ab-2; GM-Tg-bovg-MP2314-Ab-1/ GM-Tg-bovg-MP2314-Ab-2; GM-Tg-equg-MP2314-Ab-1/ GM-Tg-equg-MP2314-Ab-2 |
Products Name | Anti-S100A13 monoclonal antibody |
Format | mab |
Target Name | S100A13 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-S100A13 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species S10AD/ S100A13 VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | vGMLP000285 | human S100A13 Lentivirus particle |
ORF Viral Vector | pGMLP000285 | human S100A13 Lentivirus plasmid |
ORF Viral Vector | pGMLPm001023 | mouse S100a13 Lentivirus plasmid |
ORF Viral Vector | vGMLPm001023 | mouse S100a13 Lentivirus particle |
Target information
Target ID | GM-MP2314 |
Target Name | S100A13 |
Gene ID | 6284,20196,295213,713890,490457,101082121,404146,100056308 |
Gene Symbol and Synonyms | S100A1,S100A13 |
Uniprot Accession | Q99584,P79342 |
Uniprot Entry Name | S10AD_HUMAN,S10AD_BOVIN |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000189171 |
Target Classification | N/A |
The target: S100A13, gene name: S100A13, also named as . The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.