Anti-S10AD/ S100A13 monoclonal antibody

Anti-S10AD/ S100A13 antibody for FACS & in-vivo assay

Target products collectionGo to S100A13/S100A13 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2314-Ab-1/ GM-Tg-hg-MP2314-Ab-2Anti-Human S100A13 monoclonal antibodyHuman
GM-Tg-rg-MP2314-Ab-1/ GM-Tg-rg-MP2314-Ab-2Anti-Rat S100A13 monoclonal antibodyRat
GM-Tg-mg-MP2314-Ab-1/ GM-Tg-mg-MP2314-Ab-2Anti-Mouse S100A13 monoclonal antibodyMouse
GM-Tg-cynog-MP2314-Ab-1/ GM-Tg-cynog-MP2314-Ab-2Anti-Cynomolgus/ Rhesus macaque S100A13 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2314-Ab-1/ GM-Tg-felg-MP2314-Ab-2Anti-Feline S100A13 monoclonal antibodyFeline
GM-Tg-cang-MP2314-Ab-1/ GM-Tg-cang-MP2314-Ab-2Anti-Canine S100A13 monoclonal antibodyCanine
GM-Tg-bovg-MP2314-Ab-1/ GM-Tg-bovg-MP2314-Ab-2Anti-Bovine S100A13 monoclonal antibodyBovine
GM-Tg-equg-MP2314-Ab-1/ GM-Tg-equg-MP2314-Ab-2Anti-Equine S100A13 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2314-Ab-1/ GM-Tg-hg-MP2314-Ab-2; GM-Tg-rg-MP2314-Ab-1/ GM-Tg-rg-MP2314-Ab-2;
GM-Tg-mg-MP2314-Ab-1/ GM-Tg-mg-MP2314-Ab-2; GM-Tg-cynog-MP2314-Ab-1/ GM-Tg-cynog-MP2314-Ab-2;
GM-Tg-felg-MP2314-Ab-1/ GM-Tg-felg-MP2314-Ab-2; GM-Tg-cang-MP2314-Ab-1/ GM-Tg-cang-MP2314-Ab-2;
GM-Tg-bovg-MP2314-Ab-1/ GM-Tg-bovg-MP2314-Ab-2; GM-Tg-equg-MP2314-Ab-1/ GM-Tg-equg-MP2314-Ab-2
Products NameAnti-S100A13 monoclonal antibody
Formatmab
Target NameS100A13
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-S100A13 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species S10AD/ S100A13 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP000285human S100A13 Lentivirus particle
    ORF Viral VectorpGMLP000285human S100A13 Lentivirus plasmid
    ORF Viral VectorpGMLPm001023mouse S100a13 Lentivirus plasmid
    ORF Viral VectorvGMLPm001023mouse S100a13 Lentivirus particle


    Target information

    Target IDGM-MP2314
    Target NameS100A13
    Gene ID6284,20196,295213,713890,490457,101082121,404146,100056308
    Gene Symbol and SynonymsS100A1,S100A13
    Uniprot AccessionQ99584,P79342
    Uniprot Entry NameS10AD_HUMAN,S10AD_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000189171
    Target ClassificationN/A

    The target: S100A13, gene name: S100A13, also named as . The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.