Anti-SI1L1/ SIPA1L1/ E6TP1 monoclonal antibody

Anti-SI1L1/ SIPA1L1/ E6TP1 antibody for FACS & in-vivo assay

Target products collectionGo to SIPA1L1/SIPA1L1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2326-Ab-1/ GM-Tg-hg-MP2326-Ab-2Anti-Human SIPA1L1 monoclonal antibodyHuman
GM-Tg-rg-MP2326-Ab-1/ GM-Tg-rg-MP2326-Ab-2Anti-Rat SIPA1L1 monoclonal antibodyRat
GM-Tg-mg-MP2326-Ab-1/ GM-Tg-mg-MP2326-Ab-2Anti-Mouse SIPA1L1 monoclonal antibodyMouse
GM-Tg-cynog-MP2326-Ab-1/ GM-Tg-cynog-MP2326-Ab-2Anti-Cynomolgus/ Rhesus macaque SIPA1L1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2326-Ab-1/ GM-Tg-felg-MP2326-Ab-2Anti-Feline SIPA1L1 monoclonal antibodyFeline
GM-Tg-cang-MP2326-Ab-1/ GM-Tg-cang-MP2326-Ab-2Anti-Canine SIPA1L1 monoclonal antibodyCanine
GM-Tg-bovg-MP2326-Ab-1/ GM-Tg-bovg-MP2326-Ab-2Anti-Bovine SIPA1L1 monoclonal antibodyBovine
GM-Tg-equg-MP2326-Ab-1/ GM-Tg-equg-MP2326-Ab-2Anti-Equine SIPA1L1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2326-Ab-1/ GM-Tg-hg-MP2326-Ab-2; GM-Tg-rg-MP2326-Ab-1/ GM-Tg-rg-MP2326-Ab-2;
GM-Tg-mg-MP2326-Ab-1/ GM-Tg-mg-MP2326-Ab-2; GM-Tg-cynog-MP2326-Ab-1/ GM-Tg-cynog-MP2326-Ab-2;
GM-Tg-felg-MP2326-Ab-1/ GM-Tg-felg-MP2326-Ab-2; GM-Tg-cang-MP2326-Ab-1/ GM-Tg-cang-MP2326-Ab-2;
GM-Tg-bovg-MP2326-Ab-1/ GM-Tg-bovg-MP2326-Ab-2; GM-Tg-equg-MP2326-Ab-1/ GM-Tg-equg-MP2326-Ab-2
Products NameAnti-SIPA1L1 monoclonal antibody
Formatmab
Target NameSIPA1L1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SIPA1L1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SI1L1/ SIPA1L1/ E6TP1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2326
    Target NameSIPA1L1
    Gene ID26037,217692,246212,694485,480379,101082920,787248,100049969
    Gene Symbol and Synonyms4931426N11Rik,E6TP1,mKIAA0440,SIPA1L1,Spa-1,Spa1,SPAL,Spar,SPAR1
    Uniprot AccessionO43166,O35412
    Uniprot Entry NameSI1L1_HUMAN,SI1L1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000197555
    Target ClassificationN/A

    The target: SIPA1L1, gene name: SIPA1L1, also named as E6TP1. Predicted to enable GTPase activator activity; actin filament binding activity; and protein kinase binding activity. Predicted to be involved in several processes, including actin cytoskeleton organization; activation of GTPase activity; and regulation of postsynapse organization. Located in actin cytoskeleton and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.