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Anti-NHRF2/ SLC9A3R2/ E3KARP monoclonal antibody
Anti-NHRF2/ SLC9A3R2/ E3KARP antibody for FACS & in-vivo assay
Go to SLC9A3R2/SLC9A3R2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2330-Ab-1/ GM-Tg-hg-MP2330-Ab-2 | Anti-Human SLC9A3R2 monoclonal antibody | Human |
| GM-Tg-rg-MP2330-Ab-1/ GM-Tg-rg-MP2330-Ab-2 | Anti-Rat SLC9A3R2 monoclonal antibody | Rat |
| GM-Tg-mg-MP2330-Ab-1/ GM-Tg-mg-MP2330-Ab-2 | Anti-Mouse SLC9A3R2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2330-Ab-1/ GM-Tg-cynog-MP2330-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC9A3R2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2330-Ab-1/ GM-Tg-felg-MP2330-Ab-2 | Anti-Feline SLC9A3R2 monoclonal antibody | Feline |
| GM-Tg-cang-MP2330-Ab-1/ GM-Tg-cang-MP2330-Ab-2 | Anti-Canine SLC9A3R2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2330-Ab-1/ GM-Tg-bovg-MP2330-Ab-2 | Anti-Bovine SLC9A3R2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2330-Ab-1/ GM-Tg-equg-MP2330-Ab-2 | Anti-Equine SLC9A3R2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2330-Ab-1/ GM-Tg-hg-MP2330-Ab-2; GM-Tg-rg-MP2330-Ab-1/ GM-Tg-rg-MP2330-Ab-2; GM-Tg-mg-MP2330-Ab-1/ GM-Tg-mg-MP2330-Ab-2; GM-Tg-cynog-MP2330-Ab-1/ GM-Tg-cynog-MP2330-Ab-2; GM-Tg-felg-MP2330-Ab-1/ GM-Tg-felg-MP2330-Ab-2; GM-Tg-cang-MP2330-Ab-1/ GM-Tg-cang-MP2330-Ab-2; GM-Tg-bovg-MP2330-Ab-1/ GM-Tg-bovg-MP2330-Ab-2; GM-Tg-equg-MP2330-Ab-1/ GM-Tg-equg-MP2330-Ab-2 |
| Products Name | Anti-SLC9A3R2 monoclonal antibody |
| Format | mab |
| Target Name | SLC9A3R2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLC9A3R2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species NHRF2/ SLC9A3R2/ E3KARP VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLPm002069 | mouse Slc9a3r2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002069 | mouse Slc9a3r2 Lentivirus particle |
Target information
| Target ID | GM-MP2330 |
| Target Name | SLC9A3R2 |
| Gene ID | 9351,65962,116501,694658,479884,101082539,768005,100146142 |
| Gene Symbol and Synonyms | 0610011L07Rik,1200011K07Rik,2010007A20Rik,E3KARP,NHE3RF2,NHERF-2,NHERF2,OCTS2,SIP-1,SIP1,SLC9A3R2,Sryip1,TKA-1 |
| Uniprot Accession | Q15599,Q920G2 |
| Uniprot Entry Name | NHRF2_HUMAN,NHRF2_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000065054 |
| Target Classification | N/A |
The target: SLC9A3R2, gene name: SLC9A3R2, also named as E3KARP, NHE3RF2, NHERF-2, NHERF2, OCTS2, SIP-1, SIP1, TKA-1. This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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