Anti-SNX9/ SDP1/ SH3PX1 monoclonal antibody
Anti-SNX9/ SDP1/ SH3PX1 antibody for FACS & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-MP2334-Ab-1/ GM-Tg-hg-MP2334-Ab-2 | Anti-Human SNX9 monoclonal antibody | Human |
GM-Tg-rg-MP2334-Ab-1/ GM-Tg-rg-MP2334-Ab-2 | Anti-Rat SNX9 monoclonal antibody | Rat |
GM-Tg-mg-MP2334-Ab-1/ GM-Tg-mg-MP2334-Ab-2 | Anti-Mouse SNX9 monoclonal antibody | Mouse |
GM-Tg-cynog-MP2334-Ab-1/ GM-Tg-cynog-MP2334-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SNX9 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-MP2334-Ab-1/ GM-Tg-felg-MP2334-Ab-2 | Anti-Feline SNX9 monoclonal antibody | Feline |
GM-Tg-cang-MP2334-Ab-1/ GM-Tg-cang-MP2334-Ab-2 | Anti-Canine SNX9 monoclonal antibody | Canine |
GM-Tg-bovg-MP2334-Ab-1/ GM-Tg-bovg-MP2334-Ab-2 | Anti-Bovine SNX9 monoclonal antibody | Bovine |
GM-Tg-equg-MP2334-Ab-1/ GM-Tg-equg-MP2334-Ab-2 | Anti-Equine SNX9 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-MP2334-Ab-1/ GM-Tg-hg-MP2334-Ab-2; GM-Tg-rg-MP2334-Ab-1/ GM-Tg-rg-MP2334-Ab-2; GM-Tg-mg-MP2334-Ab-1/ GM-Tg-mg-MP2334-Ab-2; GM-Tg-cynog-MP2334-Ab-1/ GM-Tg-cynog-MP2334-Ab-2; GM-Tg-felg-MP2334-Ab-1/ GM-Tg-felg-MP2334-Ab-2; GM-Tg-cang-MP2334-Ab-1/ GM-Tg-cang-MP2334-Ab-2; GM-Tg-bovg-MP2334-Ab-1/ GM-Tg-bovg-MP2334-Ab-2; GM-Tg-equg-MP2334-Ab-1/ GM-Tg-equg-MP2334-Ab-2 |
Products Name | Anti-SNX9 monoclonal antibody |
Format | mab |
Target Name | SNX9 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-SNX9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species SNX9/ SDP1/ SH3PX1 VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | vGMLP001031 | human SNX9 Lentivirus particle |
ORF Viral Vector | pGMLP001031 | human SNX9 Lentivirus plasmid |
ORF Viral Vector | pGMLPm002739 | mouse Snx9 Lentivirus plasmid |
ORF Viral Vector | vGMLPm002739 | mouse Snx9 Lentivirus particle |
Target information
Target ID | GM-MP2334 |
Target Name | SNX9 |
Gene ID | 51429,66616,683687,706016,476254,101091537,506218,100059877 |
Gene Symbol and Synonyms | 2700073N08Rik,SDP1,SH3PX1,SH3PXD3A,SNX9,WISP |
Uniprot Accession | Q9Y5X1 |
Uniprot Entry Name | SNX9_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000130340 |
Target Classification | N/A |
The target: SNX9, gene name: SNX9, also named as SDP1, SH3PX1, SH3PXD3A, WISP. This gene encodes a member of the sorting nexin family. Members of this family contain a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein does not contain a coiled coil region, like some family members, but does contain a SRC homology domain near its N-terminus. The encoded protein is reported to have a variety of interaction partners, including of adaptor protein 2 , dynamin, tyrosine kinase non-receptor 2, Wiskott-Aldrich syndrome-like, and ARP3 actin-related protein 3. The encoded protein is implicated in several stages of intracellular trafficking, including endocytosis, macropinocytosis, and F-actin nucleation. [provided by RefSeq, Jul 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.