Anti-SNX9/ SDP1/ SH3PX1 monoclonal antibody

Anti-SNX9/ SDP1/ SH3PX1 antibody for FACS & in-vivo assay

Target products collectionGo to SNX9/SNX9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2334-Ab-1/ GM-Tg-hg-MP2334-Ab-2Anti-Human SNX9 monoclonal antibodyHuman
GM-Tg-rg-MP2334-Ab-1/ GM-Tg-rg-MP2334-Ab-2Anti-Rat SNX9 monoclonal antibodyRat
GM-Tg-mg-MP2334-Ab-1/ GM-Tg-mg-MP2334-Ab-2Anti-Mouse SNX9 monoclonal antibodyMouse
GM-Tg-cynog-MP2334-Ab-1/ GM-Tg-cynog-MP2334-Ab-2Anti-Cynomolgus/ Rhesus macaque SNX9 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2334-Ab-1/ GM-Tg-felg-MP2334-Ab-2Anti-Feline SNX9 monoclonal antibodyFeline
GM-Tg-cang-MP2334-Ab-1/ GM-Tg-cang-MP2334-Ab-2Anti-Canine SNX9 monoclonal antibodyCanine
GM-Tg-bovg-MP2334-Ab-1/ GM-Tg-bovg-MP2334-Ab-2Anti-Bovine SNX9 monoclonal antibodyBovine
GM-Tg-equg-MP2334-Ab-1/ GM-Tg-equg-MP2334-Ab-2Anti-Equine SNX9 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2334-Ab-1/ GM-Tg-hg-MP2334-Ab-2; GM-Tg-rg-MP2334-Ab-1/ GM-Tg-rg-MP2334-Ab-2;
GM-Tg-mg-MP2334-Ab-1/ GM-Tg-mg-MP2334-Ab-2; GM-Tg-cynog-MP2334-Ab-1/ GM-Tg-cynog-MP2334-Ab-2;
GM-Tg-felg-MP2334-Ab-1/ GM-Tg-felg-MP2334-Ab-2; GM-Tg-cang-MP2334-Ab-1/ GM-Tg-cang-MP2334-Ab-2;
GM-Tg-bovg-MP2334-Ab-1/ GM-Tg-bovg-MP2334-Ab-2; GM-Tg-equg-MP2334-Ab-1/ GM-Tg-equg-MP2334-Ab-2
Products NameAnti-SNX9 monoclonal antibody
Formatmab
Target NameSNX9
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SNX9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SNX9/ SDP1/ SH3PX1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP001031human SNX9 Lentivirus particle
    ORF Viral VectorpGMLP001031human SNX9 Lentivirus plasmid
    ORF Viral VectorpGMLPm002739mouse Snx9 Lentivirus plasmid
    ORF Viral VectorvGMLPm002739mouse Snx9 Lentivirus particle


    Target information

    Target IDGM-MP2334
    Target NameSNX9
    Gene ID51429,66616,683687,706016,476254,101091537,506218,100059877
    Gene Symbol and Synonyms2700073N08Rik,SDP1,SH3PX1,SH3PXD3A,SNX9,WISP
    Uniprot AccessionQ9Y5X1
    Uniprot Entry NameSNX9_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000130340
    Target ClassificationN/A

    The target: SNX9, gene name: SNX9, also named as SDP1, SH3PX1, SH3PXD3A, WISP. This gene encodes a member of the sorting nexin family. Members of this family contain a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein does not contain a coiled coil region, like some family members, but does contain a SRC homology domain near its N-terminus. The encoded protein is reported to have a variety of interaction partners, including of adaptor protein 2 , dynamin, tyrosine kinase non-receptor 2, Wiskott-Aldrich syndrome-like, and ARP3 actin-related protein 3. The encoded protein is implicated in several stages of intracellular trafficking, including endocytosis, macropinocytosis, and F-actin nucleation. [provided by RefSeq, Jul 2013].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.