Anti-SWP70/ SWAP70/ HSPC321 monoclonal antibody

Anti-SWP70/ SWAP70/ HSPC321 antibody for FACS & in-vivo assay

Target products collectionGo to SWAP70/SWAP70 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2342-Ab-1/ GM-Tg-hg-MP2342-Ab-2Anti-Human SWAP70 monoclonal antibodyHuman
GM-Tg-rg-MP2342-Ab-1/ GM-Tg-rg-MP2342-Ab-2Anti-Rat SWAP70 monoclonal antibodyRat
GM-Tg-mg-MP2342-Ab-1/ GM-Tg-mg-MP2342-Ab-2Anti-Mouse SWAP70 monoclonal antibodyMouse
GM-Tg-cynog-MP2342-Ab-1/ GM-Tg-cynog-MP2342-Ab-2Anti-Cynomolgus/ Rhesus macaque SWAP70 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2342-Ab-1/ GM-Tg-felg-MP2342-Ab-2Anti-Feline SWAP70 monoclonal antibodyFeline
GM-Tg-cang-MP2342-Ab-1/ GM-Tg-cang-MP2342-Ab-2Anti-Canine SWAP70 monoclonal antibodyCanine
GM-Tg-bovg-MP2342-Ab-1/ GM-Tg-bovg-MP2342-Ab-2Anti-Bovine SWAP70 monoclonal antibodyBovine
GM-Tg-equg-MP2342-Ab-1/ GM-Tg-equg-MP2342-Ab-2Anti-Equine SWAP70 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2342-Ab-1/ GM-Tg-hg-MP2342-Ab-2; GM-Tg-rg-MP2342-Ab-1/ GM-Tg-rg-MP2342-Ab-2;
GM-Tg-mg-MP2342-Ab-1/ GM-Tg-mg-MP2342-Ab-2; GM-Tg-cynog-MP2342-Ab-1/ GM-Tg-cynog-MP2342-Ab-2;
GM-Tg-felg-MP2342-Ab-1/ GM-Tg-felg-MP2342-Ab-2; GM-Tg-cang-MP2342-Ab-1/ GM-Tg-cang-MP2342-Ab-2;
GM-Tg-bovg-MP2342-Ab-1/ GM-Tg-bovg-MP2342-Ab-2; GM-Tg-equg-MP2342-Ab-1/ GM-Tg-equg-MP2342-Ab-2
Products NameAnti-SWAP70 monoclonal antibody
Formatmab
Target NameSWAP70
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SWAP70 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SWP70/ SWAP70/ HSPC321 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP002495human SWAP70 Lentivirus particle
    ORF Viral VectorpGMLP002495human SWAP70 Lentivirus plasmid
    ORF Viral VectorpGMLPm005222mouse Swap70 Lentivirus plasmid
    ORF Viral VectorvGMLPm005222mouse Swap70 Lentivirus particle


    Target information

    Target IDGM-MP2342
    Target NameSWAP70
    Gene ID23075,20947,293410,703651,485385,101086597,533720,100071230
    Gene Symbol and Synonyms70kDa,HSPC321,SWAP-70,SWAP70
    Uniprot AccessionQ9UH65,P0C1G6
    Uniprot Entry NameSWP70_HUMAN,SWP70_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000133789
    Target ClassificationN/A

    The target: SWAP70, gene name: SWAP70, also named as HSPC321, SWAP-70. Enables cadherin binding activity. Predicted to be involved in regulation of actin polymerization or depolymerization. Predicted to act upstream of or within isotype switching. Located in actin cytoskeleton; cytoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.