Anti-TACC2/ AZU-1/ ECTACC monoclonal antibody

Anti-TACC2/ AZU-1/ ECTACC antibody for FACS & in-vivo assay

Target products collectionGo to TACC2/TACC2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2345-Ab-1/ GM-Tg-hg-MP2345-Ab-2Anti-Human TACC2 monoclonal antibodyHuman
GM-Tg-rg-MP2345-Ab-1/ GM-Tg-rg-MP2345-Ab-2Anti-Rat TACC2 monoclonal antibodyRat
GM-Tg-mg-MP2345-Ab-1/ GM-Tg-mg-MP2345-Ab-2Anti-Mouse TACC2 monoclonal antibodyMouse
GM-Tg-cynog-MP2345-Ab-1/ GM-Tg-cynog-MP2345-Ab-2Anti-Cynomolgus/ Rhesus macaque TACC2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2345-Ab-1/ GM-Tg-felg-MP2345-Ab-2Anti-Feline TACC2 monoclonal antibodyFeline
GM-Tg-cang-MP2345-Ab-1/ GM-Tg-cang-MP2345-Ab-2Anti-Canine TACC2 monoclonal antibodyCanine
GM-Tg-bovg-MP2345-Ab-1/ GM-Tg-bovg-MP2345-Ab-2Anti-Bovine TACC2 monoclonal antibodyBovine
GM-Tg-equg-MP2345-Ab-1/ GM-Tg-equg-MP2345-Ab-2Anti-Equine TACC2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2345-Ab-1/ GM-Tg-hg-MP2345-Ab-2; GM-Tg-rg-MP2345-Ab-1/ GM-Tg-rg-MP2345-Ab-2;
GM-Tg-mg-MP2345-Ab-1/ GM-Tg-mg-MP2345-Ab-2; GM-Tg-cynog-MP2345-Ab-1/ GM-Tg-cynog-MP2345-Ab-2;
GM-Tg-felg-MP2345-Ab-1/ GM-Tg-felg-MP2345-Ab-2; GM-Tg-cang-MP2345-Ab-1/ GM-Tg-cang-MP2345-Ab-2;
GM-Tg-bovg-MP2345-Ab-1/ GM-Tg-bovg-MP2345-Ab-2; GM-Tg-equg-MP2345-Ab-1/ GM-Tg-equg-MP2345-Ab-2
Products NameAnti-TACC2 monoclonal antibody
Formatmab
Target NameTACC2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TACC2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TACC2/ AZU-1/ ECTACC VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2345
    Target NameTACC2
    Gene ID10579,57752,309025,705497,477850,101090968,533768,100064696
    Gene Symbol and SynonymsAZU-1,ECTACC,mKIAA4180,TACC2
    Uniprot AccessionO95359
    Uniprot Entry NameTACC2_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000138162
    Target ClassificationN/A

    The target: TACC2, gene name: TACC2, also named as AZU-1, ECTACC. Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is induced by erythropoietin and is thought to affect the progression of breast tumors. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.