Anti-TCHP/ TpMs monoclonal antibody

Anti-TCHP/ TpMs antibody for FACS & in-vivo assay

Target products collectionGo to TCHP/TCHP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2350-Ab-1/ GM-Tg-hg-MP2350-Ab-2Anti-Human TCHP monoclonal antibodyHuman
GM-Tg-rg-MP2350-Ab-1/ GM-Tg-rg-MP2350-Ab-2Anti-Rat TCHP monoclonal antibodyRat
GM-Tg-mg-MP2350-Ab-1/ GM-Tg-mg-MP2350-Ab-2Anti-Mouse TCHP monoclonal antibodyMouse
GM-Tg-cynog-MP2350-Ab-1/ GM-Tg-cynog-MP2350-Ab-2Anti-Cynomolgus/ Rhesus macaque TCHP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2350-Ab-1/ GM-Tg-felg-MP2350-Ab-2Anti-Feline TCHP monoclonal antibodyFeline
GM-Tg-cang-MP2350-Ab-1/ GM-Tg-cang-MP2350-Ab-2Anti-Canine TCHP monoclonal antibodyCanine
GM-Tg-bovg-MP2350-Ab-1/ GM-Tg-bovg-MP2350-Ab-2Anti-Bovine TCHP monoclonal antibodyBovine
GM-Tg-equg-MP2350-Ab-1/ GM-Tg-equg-MP2350-Ab-2Anti-Equine TCHP monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2350-Ab-1/ GM-Tg-hg-MP2350-Ab-2; GM-Tg-rg-MP2350-Ab-1/ GM-Tg-rg-MP2350-Ab-2;
GM-Tg-mg-MP2350-Ab-1/ GM-Tg-mg-MP2350-Ab-2; GM-Tg-cynog-MP2350-Ab-1/ GM-Tg-cynog-MP2350-Ab-2;
GM-Tg-felg-MP2350-Ab-1/ GM-Tg-felg-MP2350-Ab-2; GM-Tg-cang-MP2350-Ab-1/ GM-Tg-cang-MP2350-Ab-2;
GM-Tg-bovg-MP2350-Ab-1/ GM-Tg-bovg-MP2350-Ab-2; GM-Tg-equg-MP2350-Ab-1/ GM-Tg-equg-MP2350-Ab-2
Products NameAnti-TCHP monoclonal antibody
Formatmab
Target NameTCHP
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TCHP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TCHP/ TpMs VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2350
    Target NameTCHP
    Gene ID84260,77832,304547,720897,477521,101084393,522380,100059689
    Gene Symbol and SynonymsA930031F18Rik,RGD1310813,TCHP,TpMs
    Uniprot AccessionQ9BT92
    Uniprot Entry NameTCHP_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000139437
    Target ClassificationN/A

    The target: TCHP, gene name: TCHP, also named as TpMs. Involved in apoptotic process; negative regulation of cell growth; and negative regulation of cilium assembly. Located in several cellular components, including apical cortex; cytoskeleton; and mitochondrion. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.