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Anti-TRAF7/ RFWD1/ RNF119 monoclonal antibody
Anti-TRAF7/ RFWD1/ RNF119 antibody for FACS & in-vivo assay
Go to TRAF7/TRAF7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2358-Ab-1/ GM-Tg-hg-MP2358-Ab-2 | Anti-Human TRAF7 monoclonal antibody | Human |
| GM-Tg-rg-MP2358-Ab-1/ GM-Tg-rg-MP2358-Ab-2 | Anti-Rat TRAF7 monoclonal antibody | Rat |
| GM-Tg-mg-MP2358-Ab-1/ GM-Tg-mg-MP2358-Ab-2 | Anti-Mouse TRAF7 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2358-Ab-1/ GM-Tg-cynog-MP2358-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TRAF7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2358-Ab-1/ GM-Tg-felg-MP2358-Ab-2 | Anti-Feline TRAF7 monoclonal antibody | Feline |
| GM-Tg-cang-MP2358-Ab-1/ GM-Tg-cang-MP2358-Ab-2 | Anti-Canine TRAF7 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2358-Ab-1/ GM-Tg-bovg-MP2358-Ab-2 | Anti-Bovine TRAF7 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2358-Ab-1/ GM-Tg-equg-MP2358-Ab-2 | Anti-Equine TRAF7 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2358-Ab-1/ GM-Tg-hg-MP2358-Ab-2; GM-Tg-rg-MP2358-Ab-1/ GM-Tg-rg-MP2358-Ab-2; GM-Tg-mg-MP2358-Ab-1/ GM-Tg-mg-MP2358-Ab-2; GM-Tg-cynog-MP2358-Ab-1/ GM-Tg-cynog-MP2358-Ab-2; GM-Tg-felg-MP2358-Ab-1/ GM-Tg-felg-MP2358-Ab-2; GM-Tg-cang-MP2358-Ab-1/ GM-Tg-cang-MP2358-Ab-2; GM-Tg-bovg-MP2358-Ab-1/ GM-Tg-bovg-MP2358-Ab-2; GM-Tg-equg-MP2358-Ab-1/ GM-Tg-equg-MP2358-Ab-2 |
| Products Name | Anti-TRAF7 monoclonal antibody |
| Format | mab |
| Target Name | TRAF7 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-TRAF7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species TRAF7/ RFWD1/ RNF119 VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-MP2358-Ag-1 | TNF receptor-associated factor 7, E3 ubiquitin protein ligase (TRAF7) protein |
| ORF Viral Vector | vGMLP001174 | human TRAF7 Lentivirus particle |
| ORF Viral Vector | pGMLP001174 | human TRAF7 Lentivirus plasmid |
| ORF Viral Vector | pGMAD000082 | mouse Traf7 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000082 | mouse Traf7 Adenovirus particle |
Target information
| Target ID | GM-MP2358 |
| Target Name | TRAF7 |
| Gene ID | 84231,224619,360491,695415,609824,101082031,511692,100065698 |
| Gene Symbol and Synonyms | CAFDADD,RFWD1,RGD1559653,RNF119,TRAF7 |
| Uniprot Accession | Q6Q0C0 |
| Uniprot Entry Name | TRAF7_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000131653 |
| Target Classification | N/A |
The target: TRAF7, gene name: TRAF7, also named as RFWD1, RNF119. Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.[supplied by OMIM, Apr 2004].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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