Anti-TRI16/ TRIM16/ EBBP monoclonal antibody

Anti-TRI16/ TRIM16/ EBBP antibody for FACS & in-vivo assay

Target products collectionGo to TRIM16/TRIM16 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2359-Ab-1/ GM-Tg-hg-MP2359-Ab-2Anti-Human TRIM16 monoclonal antibodyHuman
GM-Tg-rg-MP2359-Ab-1/ GM-Tg-rg-MP2359-Ab-2Anti-Rat TRIM16 monoclonal antibodyRat
GM-Tg-mg-MP2359-Ab-1/ GM-Tg-mg-MP2359-Ab-2Anti-Mouse TRIM16 monoclonal antibodyMouse
GM-Tg-cynog-MP2359-Ab-1/ GM-Tg-cynog-MP2359-Ab-2Anti-Cynomolgus/ Rhesus macaque TRIM16 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2359-Ab-1/ GM-Tg-felg-MP2359-Ab-2Anti-Feline TRIM16 monoclonal antibodyFeline
GM-Tg-cang-MP2359-Ab-1/ GM-Tg-cang-MP2359-Ab-2Anti-Canine TRIM16 monoclonal antibodyCanine
GM-Tg-bovg-MP2359-Ab-1/ GM-Tg-bovg-MP2359-Ab-2Anti-Bovine TRIM16 monoclonal antibodyBovine
GM-Tg-equg-MP2359-Ab-1/ GM-Tg-equg-MP2359-Ab-2Anti-Equine TRIM16 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2359-Ab-1/ GM-Tg-hg-MP2359-Ab-2; GM-Tg-rg-MP2359-Ab-1/ GM-Tg-rg-MP2359-Ab-2;
GM-Tg-mg-MP2359-Ab-1/ GM-Tg-mg-MP2359-Ab-2; GM-Tg-cynog-MP2359-Ab-1/ GM-Tg-cynog-MP2359-Ab-2;
GM-Tg-felg-MP2359-Ab-1/ GM-Tg-felg-MP2359-Ab-2; GM-Tg-cang-MP2359-Ab-1/ GM-Tg-cang-MP2359-Ab-2;
GM-Tg-bovg-MP2359-Ab-1/ GM-Tg-bovg-MP2359-Ab-2; GM-Tg-equg-MP2359-Ab-1/ GM-Tg-equg-MP2359-Ab-2
Products NameAnti-TRIM16 monoclonal antibody
Formatmab
Target NameTRIM16
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TRIM16 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TRI16/ TRIM16/ EBBP VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2359
    Target NameTRIM16
    Gene ID10626,94092,303214,106993901,489518,101090812,100848152,100146229
    Gene Symbol and Synonyms9130006M08Rik,EBBP,TRIM16
    Uniprot AccessionO95361
    Uniprot Entry NameTRI16_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000221926
    Target ClassificationN/A

    The target: TRIM16, gene name: TRIM16, also named as EBBP. The protein encoded by this gene is a tripartite motif (TRIM) family member that contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. While it lacks a RING domain found in other TRIM proteins, the encoded protein can homodimerize or heterodimerize with other TRIM proteins and has E3 ubiquitin ligase activity. This gene is also a tumor suppressor and is involved in secretory autophagy. [provided by RefSeq, Jan 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.