Anti-TRIM4/ RNF87 monoclonal antibody

Anti-TRIM4/ RNF87 antibody for FACS & in-vivo assay

Target products collectionGo to TRIM4/TRIM4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2361-Ab-1/ GM-Tg-hg-MP2361-Ab-2Anti-Human TRIM4 monoclonal antibodyHuman
GM-Tg-rg-MP2361-Ab-1/ GM-Tg-rg-MP2361-Ab-2Anti-Rat TRIM4 monoclonal antibodyRat
GM-Tg-mg-MP2361-Ab-1/ GM-Tg-mg-MP2361-Ab-2Anti-Mouse TRIM4 monoclonal antibodyMouse
GM-Tg-cynog-MP2361-Ab-1/ GM-Tg-cynog-MP2361-Ab-2Anti-Cynomolgus/ Rhesus macaque TRIM4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2361-Ab-1/ GM-Tg-felg-MP2361-Ab-2Anti-Feline TRIM4 monoclonal antibodyFeline
GM-Tg-cang-MP2361-Ab-1/ GM-Tg-cang-MP2361-Ab-2Anti-Canine TRIM4 monoclonal antibodyCanine
GM-Tg-bovg-MP2361-Ab-1/ GM-Tg-bovg-MP2361-Ab-2Anti-Bovine TRIM4 monoclonal antibodyBovine
GM-Tg-equg-MP2361-Ab-1/ GM-Tg-equg-MP2361-Ab-2Anti-Equine TRIM4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2361-Ab-1/ GM-Tg-hg-MP2361-Ab-2; GM-Tg-rg-MP2361-Ab-1/ GM-Tg-rg-MP2361-Ab-2;
GM-Tg-mg-MP2361-Ab-1/ GM-Tg-mg-MP2361-Ab-2; GM-Tg-cynog-MP2361-Ab-1/ GM-Tg-cynog-MP2361-Ab-2;
GM-Tg-felg-MP2361-Ab-1/ GM-Tg-felg-MP2361-Ab-2; GM-Tg-cang-MP2361-Ab-1/ GM-Tg-cang-MP2361-Ab-2;
GM-Tg-bovg-MP2361-Ab-1/ GM-Tg-bovg-MP2361-Ab-2; GM-Tg-equg-MP2361-Ab-1/ GM-Tg-equg-MP2361-Ab-2
Products NameAnti-TRIM4 monoclonal antibody
Formatmab
Target NameTRIM4
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TRIM4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TRIM4/ RNF87 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2361
    Target NameTRIM4
    Gene ID89122,709962,608654,101097197,527577,102147803
    Gene Symbol and SynonymsRNF87,TRIM4
    Uniprot AccessionQ9C037
    Uniprot Entry NameTRIM4_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000146833
    Target ClassificationN/A

    The target: TRIM4, gene name: TRIM4, also named as RNF87. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternatively spliced transcript variants that encode different isoforms have been described.[provided by RefSeq, Jul 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.