Anti-TTC7B/ TTC7L1/ c14_5685 monoclonal antibody

Anti-TTC7B/ TTC7L1/ c14_5685 antibody for FACS & in-vivo assay

Target products collectionGo to TTC7B/TTC7B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2364-Ab-1/ GM-Tg-hg-MP2364-Ab-2Anti-Human TTC7B monoclonal antibodyHuman
GM-Tg-rg-MP2364-Ab-1/ GM-Tg-rg-MP2364-Ab-2Anti-Rat TTC7B monoclonal antibodyRat
GM-Tg-mg-MP2364-Ab-1/ GM-Tg-mg-MP2364-Ab-2Anti-Mouse TTC7B monoclonal antibodyMouse
GM-Tg-cynog-MP2364-Ab-1/ GM-Tg-cynog-MP2364-Ab-2Anti-Cynomolgus/ Rhesus macaque TTC7B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2364-Ab-1/ GM-Tg-felg-MP2364-Ab-2Anti-Feline TTC7B monoclonal antibodyFeline
GM-Tg-cang-MP2364-Ab-1/ GM-Tg-cang-MP2364-Ab-2Anti-Canine TTC7B monoclonal antibodyCanine
GM-Tg-bovg-MP2364-Ab-1/ GM-Tg-bovg-MP2364-Ab-2Anti-Bovine TTC7B monoclonal antibodyBovine
GM-Tg-equg-MP2364-Ab-1/ GM-Tg-equg-MP2364-Ab-2Anti-Equine TTC7B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2364-Ab-1/ GM-Tg-hg-MP2364-Ab-2; GM-Tg-rg-MP2364-Ab-1/ GM-Tg-rg-MP2364-Ab-2;
GM-Tg-mg-MP2364-Ab-1/ GM-Tg-mg-MP2364-Ab-2; GM-Tg-cynog-MP2364-Ab-1/ GM-Tg-cynog-MP2364-Ab-2;
GM-Tg-felg-MP2364-Ab-1/ GM-Tg-felg-MP2364-Ab-2; GM-Tg-cang-MP2364-Ab-1/ GM-Tg-cang-MP2364-Ab-2;
GM-Tg-bovg-MP2364-Ab-1/ GM-Tg-bovg-MP2364-Ab-2; GM-Tg-equg-MP2364-Ab-1/ GM-Tg-equg-MP2364-Ab-2
Products NameAnti-TTC7B monoclonal antibody
Formatmab
Target NameTTC7B
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TTC7B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TTC7B/ TTC7L1/ c14_5685 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2364
    Target NameTTC7B
    Gene ID145567,104718,362768,696029,480417,101094934,616909,100062817
    Gene Symbol and Synonymsc14_5685,TTC7B,TTC7L1
    Uniprot AccessionQ86TV6
    Uniprot Entry NameTTC7B_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000165914
    Target ClassificationN/A

    The target: TTC7B, gene name: TTC7B, also named as TTC7L1, c14_5685. Involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.