Anti-TTLL5/ CORD19/ KIAA0998 monoclonal antibody

Anti-TTLL5/ CORD19/ KIAA0998 antibody for FACS & in-vivo assay

Target products collectionGo to TTLL5/TTLL5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2365-Ab-1/ GM-Tg-hg-MP2365-Ab-2Anti-Human TTLL5 monoclonal antibodyHuman
GM-Tg-rg-MP2365-Ab-1/ GM-Tg-rg-MP2365-Ab-2Anti-Rat TTLL5 monoclonal antibodyRat
GM-Tg-mg-MP2365-Ab-1/ GM-Tg-mg-MP2365-Ab-2Anti-Mouse TTLL5 monoclonal antibodyMouse
GM-Tg-cynog-MP2365-Ab-1/ GM-Tg-cynog-MP2365-Ab-2Anti-Cynomolgus/ Rhesus macaque TTLL5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2365-Ab-1/ GM-Tg-felg-MP2365-Ab-2Anti-Feline TTLL5 monoclonal antibodyFeline
GM-Tg-cang-MP2365-Ab-1/ GM-Tg-cang-MP2365-Ab-2Anti-Canine TTLL5 monoclonal antibodyCanine
GM-Tg-bovg-MP2365-Ab-1/ GM-Tg-bovg-MP2365-Ab-2Anti-Bovine TTLL5 monoclonal antibodyBovine
GM-Tg-equg-MP2365-Ab-1/ GM-Tg-equg-MP2365-Ab-2Anti-Equine TTLL5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2365-Ab-1/ GM-Tg-hg-MP2365-Ab-2; GM-Tg-rg-MP2365-Ab-1/ GM-Tg-rg-MP2365-Ab-2;
GM-Tg-mg-MP2365-Ab-1/ GM-Tg-mg-MP2365-Ab-2; GM-Tg-cynog-MP2365-Ab-1/ GM-Tg-cynog-MP2365-Ab-2;
GM-Tg-felg-MP2365-Ab-1/ GM-Tg-felg-MP2365-Ab-2; GM-Tg-cang-MP2365-Ab-1/ GM-Tg-cang-MP2365-Ab-2;
GM-Tg-bovg-MP2365-Ab-1/ GM-Tg-bovg-MP2365-Ab-2; GM-Tg-equg-MP2365-Ab-1/ GM-Tg-equg-MP2365-Ab-2
Products NameAnti-TTLL5 monoclonal antibody
Formatmab
Target NameTTLL5
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TTLL5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TTLL5/ CORD19/ KIAA0998 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2365
    Target NameTTLL5
    Gene ID23093,320244,299208,703116,480394,101084291,538422,100051705
    Gene Symbol and Synonyms1700048H13Rik,2310009M18Rik,4930556H18Rik,CORD19,D630041K24Rik,KIAA0998,mKIAA0998,RGD1563583,STAMP,TTLL5
    Uniprot AccessionQ6EMB2
    Uniprot Entry NameTTLL5_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000119685
    Target ClassificationN/A

    The target: TTLL5, gene name: TTLL5, also named as CORD19, KIAA0998, STAMP. This gene encodes a member of the tubulin tyrosine ligase like protein family. This protein interacts with two glucocorticoid receptor coactivators, transcriptional intermediary factor 2 and steroid receptor coactivator 1. This protein may function as a coregulator of glucocorticoid receptor mediated gene induction and repression. This protein may also function as an alpha tubulin polyglutamylase.[provided by RefSeq, Feb 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.