Anti-UAP1/ AGX/ AGX1 monoclonal antibody

Anti-UAP1/ AGX/ AGX1 antibody for FACS & in-vivo assay

Target products collectionGo to UAP1/UAP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2367-Ab-1/ GM-Tg-hg-MP2367-Ab-2Anti-Human UAP1 monoclonal antibodyHuman
GM-Tg-rg-MP2367-Ab-1/ GM-Tg-rg-MP2367-Ab-2Anti-Rat UAP1 monoclonal antibodyRat
GM-Tg-mg-MP2367-Ab-1/ GM-Tg-mg-MP2367-Ab-2Anti-Mouse UAP1 monoclonal antibodyMouse
GM-Tg-cynog-MP2367-Ab-1/ GM-Tg-cynog-MP2367-Ab-2Anti-Cynomolgus/ Rhesus macaque UAP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2367-Ab-1/ GM-Tg-felg-MP2367-Ab-2Anti-Feline UAP1 monoclonal antibodyFeline
GM-Tg-cang-MP2367-Ab-1/ GM-Tg-cang-MP2367-Ab-2Anti-Canine UAP1 monoclonal antibodyCanine
GM-Tg-bovg-MP2367-Ab-1/ GM-Tg-bovg-MP2367-Ab-2Anti-Bovine UAP1 monoclonal antibodyBovine
GM-Tg-equg-MP2367-Ab-1/ GM-Tg-equg-MP2367-Ab-2Anti-Equine UAP1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2367-Ab-1/ GM-Tg-hg-MP2367-Ab-2; GM-Tg-rg-MP2367-Ab-1/ GM-Tg-rg-MP2367-Ab-2;
GM-Tg-mg-MP2367-Ab-1/ GM-Tg-mg-MP2367-Ab-2; GM-Tg-cynog-MP2367-Ab-1/ GM-Tg-cynog-MP2367-Ab-2;
GM-Tg-felg-MP2367-Ab-1/ GM-Tg-felg-MP2367-Ab-2; GM-Tg-cang-MP2367-Ab-1/ GM-Tg-cang-MP2367-Ab-2;
GM-Tg-bovg-MP2367-Ab-1/ GM-Tg-bovg-MP2367-Ab-2; GM-Tg-equg-MP2367-Ab-1/ GM-Tg-equg-MP2367-Ab-2
Products NameAnti-UAP1 monoclonal antibody
Formatmab
Target NameUAP1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-UAP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species UAP1/ AGX/ AGX1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2367
    Target NameUAP1
    Gene ID6675,107652,498272,720116,488664,101083738,535325
    Gene Symbol and SynonymsAGX,AGX-1,AGX-2,AGX1,AGX2,ES™38,RGD1561967,SPAG2,UAP1
    Uniprot AccessionQ16222
    Uniprot Entry NameUAP1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000117143
    Target ClassificationN/A

    The target: UAP1, gene name: UAP1, also named as AGX, AGX1, AGX2, SPAG2. Enables identical protein binding activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.