- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-UB2D3/ UBE2D3/ E2(17)KB3 monoclonal antibody
Anti-UB2D3/ UBE2D3/ E2(17)KB3 antibody for FACS & in-vivo assay
Go to UBE2D3/UBE2D3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2373-Ab-1/ GM-Tg-hg-MP2373-Ab-2 | Anti-Human UBE2D3 monoclonal antibody | Human |
| GM-Tg-rg-MP2373-Ab-1/ GM-Tg-rg-MP2373-Ab-2 | Anti-Rat UBE2D3 monoclonal antibody | Rat |
| GM-Tg-mg-MP2373-Ab-1/ GM-Tg-mg-MP2373-Ab-2 | Anti-Mouse UBE2D3 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2373-Ab-1/ GM-Tg-cynog-MP2373-Ab-2 | Anti-Cynomolgus/ Rhesus macaque UBE2D3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2373-Ab-1/ GM-Tg-felg-MP2373-Ab-2 | Anti-Feline UBE2D3 monoclonal antibody | Feline |
| GM-Tg-cang-MP2373-Ab-1/ GM-Tg-cang-MP2373-Ab-2 | Anti-Canine UBE2D3 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2373-Ab-1/ GM-Tg-bovg-MP2373-Ab-2 | Anti-Bovine UBE2D3 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2373-Ab-1/ GM-Tg-equg-MP2373-Ab-2 | Anti-Equine UBE2D3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2373-Ab-1/ GM-Tg-hg-MP2373-Ab-2; GM-Tg-rg-MP2373-Ab-1/ GM-Tg-rg-MP2373-Ab-2; GM-Tg-mg-MP2373-Ab-1/ GM-Tg-mg-MP2373-Ab-2; GM-Tg-cynog-MP2373-Ab-1/ GM-Tg-cynog-MP2373-Ab-2; GM-Tg-felg-MP2373-Ab-1/ GM-Tg-felg-MP2373-Ab-2; GM-Tg-cang-MP2373-Ab-1/ GM-Tg-cang-MP2373-Ab-2; GM-Tg-bovg-MP2373-Ab-1/ GM-Tg-bovg-MP2373-Ab-2; GM-Tg-equg-MP2373-Ab-1/ GM-Tg-equg-MP2373-Ab-2 |
| Products Name | Anti-UBE2D3 monoclonal antibody |
| Format | mab |
| Target Name | UBE2D3 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-UBE2D3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species UB2D3/ UBE2D3/ E2(17)KB3 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMAD000155 | human UBE2D3 Adenovirus particle |
| ORF Viral Vector | pGMAD000155 | human UBE2D3 Adenovirus plasmid |
| ORF Viral Vector | pGMLPm000018 | mouse Ube2d3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000018 | mouse Ube2d3 Lentivirus particle |
Target information
| Target ID | GM-MP2373 |
| Target Name | UBE2D3 |
| Gene ID | 7323,66105,81920,710772,478495,101094845,326583,100630481 |
| Gene Symbol and Synonyms | 1100001F19Rik,9430029A22Rik,E2(17)KB3,UBC4/5,UBCH5C,UBE2D3,UBE2D3P |
| Uniprot Accession | P61077,P61078,Q3ZCF7 |
| Uniprot Entry Name | UB2D3_HUMAN,UB2D3_RAT,UB2D3_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000109332 |
| Target Classification | N/A |
The target: UBE2D3, gene name: UBE2D3, also named as E2(17)KB3, UBC4/5, UBCH5C. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. [provided by RefSeq, Jan 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
