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Anti-UBP21/ USP21/ USP16 monoclonal antibody
Anti-UBP21/ USP21/ USP16 antibody for FACS & in-vivo assay
Go to USP21/USP21 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2376-Ab-1/ GM-Tg-hg-MP2376-Ab-2 | Anti-Human USP21 monoclonal antibody | Human |
| GM-Tg-rg-MP2376-Ab-1/ GM-Tg-rg-MP2376-Ab-2 | Anti-Rat USP21 monoclonal antibody | Rat |
| GM-Tg-mg-MP2376-Ab-1/ GM-Tg-mg-MP2376-Ab-2 | Anti-Mouse USP21 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2376-Ab-1/ GM-Tg-cynog-MP2376-Ab-2 | Anti-Cynomolgus/ Rhesus macaque USP21 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2376-Ab-1/ GM-Tg-felg-MP2376-Ab-2 | Anti-Feline USP21 monoclonal antibody | Feline |
| GM-Tg-cang-MP2376-Ab-1/ GM-Tg-cang-MP2376-Ab-2 | Anti-Canine USP21 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2376-Ab-1/ GM-Tg-bovg-MP2376-Ab-2 | Anti-Bovine USP21 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2376-Ab-1/ GM-Tg-equg-MP2376-Ab-2 | Anti-Equine USP21 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2376-Ab-1/ GM-Tg-hg-MP2376-Ab-2; GM-Tg-rg-MP2376-Ab-1/ GM-Tg-rg-MP2376-Ab-2; GM-Tg-mg-MP2376-Ab-1/ GM-Tg-mg-MP2376-Ab-2; GM-Tg-cynog-MP2376-Ab-1/ GM-Tg-cynog-MP2376-Ab-2; GM-Tg-felg-MP2376-Ab-1/ GM-Tg-felg-MP2376-Ab-2; GM-Tg-cang-MP2376-Ab-1/ GM-Tg-cang-MP2376-Ab-2; GM-Tg-bovg-MP2376-Ab-1/ GM-Tg-bovg-MP2376-Ab-2; GM-Tg-equg-MP2376-Ab-1/ GM-Tg-equg-MP2376-Ab-2 |
| Products Name | Anti-USP21 monoclonal antibody |
| Format | mab |
| Target Name | USP21 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-USP21 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species UBP21/ USP21/ USP16 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLPm003171 | mouse Usp21 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003171 | mouse Usp21 Lentivirus particle |
Target information
| Target ID | GM-MP2376 |
| Target Name | USP21 |
| Gene ID | 27005,30941,688466,719894,478979,101090585,534273,100066197 |
| Gene Symbol and Synonyms | ES™28,USP16,USP21,USP23 |
| Uniprot Accession | Q9UK80,B2GUX4,Q2KJ72 |
| Uniprot Entry Name | UBP21_HUMAN,UBP21_RAT,UBP21_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000143258 |
| Target Classification | N/A |
The target: USP21, gene name: USP21, also named as USP16, USP23. This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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