Anti-UTP20/ 1A6/DRIM/ DRIM monoclonal antibody

Anti-UTP20/ 1A6/DRIM/ DRIM antibody for FACS & in-vivo assay

Target products collectionGo to UTP20/UTP20 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2378-Ab-1/ GM-Tg-hg-MP2378-Ab-2Anti-Human UTP20 monoclonal antibodyHuman
GM-Tg-rg-MP2378-Ab-1/ GM-Tg-rg-MP2378-Ab-2Anti-Rat UTP20 monoclonal antibodyRat
GM-Tg-mg-MP2378-Ab-1/ GM-Tg-mg-MP2378-Ab-2Anti-Mouse UTP20 monoclonal antibodyMouse
GM-Tg-cynog-MP2378-Ab-1/ GM-Tg-cynog-MP2378-Ab-2Anti-Cynomolgus/ Rhesus macaque UTP20 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2378-Ab-1/ GM-Tg-felg-MP2378-Ab-2Anti-Feline UTP20 monoclonal antibodyFeline
GM-Tg-cang-MP2378-Ab-1/ GM-Tg-cang-MP2378-Ab-2Anti-Canine UTP20 monoclonal antibodyCanine
GM-Tg-bovg-MP2378-Ab-1/ GM-Tg-bovg-MP2378-Ab-2Anti-Bovine UTP20 monoclonal antibodyBovine
GM-Tg-equg-MP2378-Ab-1/ GM-Tg-equg-MP2378-Ab-2Anti-Equine UTP20 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2378-Ab-1/ GM-Tg-hg-MP2378-Ab-2; GM-Tg-rg-MP2378-Ab-1/ GM-Tg-rg-MP2378-Ab-2;
GM-Tg-mg-MP2378-Ab-1/ GM-Tg-mg-MP2378-Ab-2; GM-Tg-cynog-MP2378-Ab-1/ GM-Tg-cynog-MP2378-Ab-2;
GM-Tg-felg-MP2378-Ab-1/ GM-Tg-felg-MP2378-Ab-2; GM-Tg-cang-MP2378-Ab-1/ GM-Tg-cang-MP2378-Ab-2;
GM-Tg-bovg-MP2378-Ab-1/ GM-Tg-bovg-MP2378-Ab-2; GM-Tg-equg-MP2378-Ab-1/ GM-Tg-equg-MP2378-Ab-2
Products NameAnti-UTP20 monoclonal antibody
Formatmab
Target NameUTP20
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-UTP20 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species UTP20/ 1A6/DRIM/ DRIM VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2378
    Target NameUTP20
    Gene ID27340,70683,314713,696472,475441,101098727,510487,100052925
    Gene Symbol and Synonyms1A6/DRIM,3830408P06Rik,DRIM,mDRIM,mDRIN,RGD1560606,UTP20
    Uniprot AccessionO75691
    Uniprot Entry NameUTP20_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000120800
    Target ClassificationN/A

    The target: UTP20, gene name: UTP20, also named as 1A6/DRIM, DRIM. UTP20 is a component of the U3 small nucleolar RNA (snoRNA) (SNORD3A; MIM 180710) protein complex (U3 snoRNP) and is involved in 18S rRNA processing (Wang et al., 2007 [PubMed 17498821]).[supplied by OMIM, Jun 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.