Anti-VILI/ VIL1/ D2S1471 monoclonal antibody

Anti-VILI/ VIL1/ D2S1471 antibody for FACS & in-vivo assay

Target products collectionGo to VIL1/VIL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2380-Ab-1/ GM-Tg-hg-MP2380-Ab-2Anti-Human VIL1 monoclonal antibodyHuman
GM-Tg-rg-MP2380-Ab-1/ GM-Tg-rg-MP2380-Ab-2Anti-Rat VIL1 monoclonal antibodyRat
GM-Tg-mg-MP2380-Ab-1/ GM-Tg-mg-MP2380-Ab-2Anti-Mouse VIL1 monoclonal antibodyMouse
GM-Tg-cynog-MP2380-Ab-1/ GM-Tg-cynog-MP2380-Ab-2Anti-Cynomolgus/ Rhesus macaque VIL1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2380-Ab-1/ GM-Tg-felg-MP2380-Ab-2Anti-Feline VIL1 monoclonal antibodyFeline
GM-Tg-cang-MP2380-Ab-1/ GM-Tg-cang-MP2380-Ab-2Anti-Canine VIL1 monoclonal antibodyCanine
GM-Tg-bovg-MP2380-Ab-1/ GM-Tg-bovg-MP2380-Ab-2Anti-Bovine VIL1 monoclonal antibodyBovine
GM-Tg-equg-MP2380-Ab-1/ GM-Tg-equg-MP2380-Ab-2Anti-Equine VIL1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2380-Ab-1/ GM-Tg-hg-MP2380-Ab-2; GM-Tg-rg-MP2380-Ab-1/ GM-Tg-rg-MP2380-Ab-2;
GM-Tg-mg-MP2380-Ab-1/ GM-Tg-mg-MP2380-Ab-2; GM-Tg-cynog-MP2380-Ab-1/ GM-Tg-cynog-MP2380-Ab-2;
GM-Tg-felg-MP2380-Ab-1/ GM-Tg-felg-MP2380-Ab-2; GM-Tg-cang-MP2380-Ab-1/ GM-Tg-cang-MP2380-Ab-2;
GM-Tg-bovg-MP2380-Ab-1/ GM-Tg-bovg-MP2380-Ab-2; GM-Tg-equg-MP2380-Ab-1/ GM-Tg-equg-MP2380-Ab-2
Products NameAnti-VIL1 monoclonal antibody
Formatmab
Target NameVIL1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-VIL1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species VILI/ VIL1/ D2S1471 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2380
    Target NameVIL1
    Gene ID7429,22349,316521,698946,488522,101087511,281573,100058581
    Gene Symbol and SynonymsD2S1471,VIL,VIL1
    Uniprot AccessionP09327,Q3SZP7
    Uniprot Entry NameVILI_HUMAN,VILI_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000127831
    Target ClassificationN/A

    The target: VIL1, gene name: VIL1, also named as D2S1471, VIL. This gene encodes a member of a family of calcium-regulated actin-binding proteins.  This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments.  Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.