Anti-ZGPAT/ GPATC6/ GPATCH6 monoclonal antibody

Anti-ZGPAT/ GPATC6/ GPATCH6 antibody for FACS & in-vivo assay

Target products collectionGo to ZGPAT/ZGPAT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2392-Ab-1/ GM-Tg-hg-MP2392-Ab-2Anti-Human ZGPAT monoclonal antibodyHuman
GM-Tg-rg-MP2392-Ab-1/ GM-Tg-rg-MP2392-Ab-2Anti-Rat ZGPAT monoclonal antibodyRat
GM-Tg-mg-MP2392-Ab-1/ GM-Tg-mg-MP2392-Ab-2Anti-Mouse ZGPAT monoclonal antibodyMouse
GM-Tg-cynog-MP2392-Ab-1/ GM-Tg-cynog-MP2392-Ab-2Anti-Cynomolgus/ Rhesus macaque ZGPAT monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2392-Ab-1/ GM-Tg-felg-MP2392-Ab-2Anti-Feline ZGPAT monoclonal antibodyFeline
GM-Tg-cang-MP2392-Ab-1/ GM-Tg-cang-MP2392-Ab-2Anti-Canine ZGPAT monoclonal antibodyCanine
GM-Tg-bovg-MP2392-Ab-1/ GM-Tg-bovg-MP2392-Ab-2Anti-Bovine ZGPAT monoclonal antibodyBovine
GM-Tg-equg-MP2392-Ab-1/ GM-Tg-equg-MP2392-Ab-2Anti-Equine ZGPAT monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2392-Ab-1/ GM-Tg-hg-MP2392-Ab-2; GM-Tg-rg-MP2392-Ab-1/ GM-Tg-rg-MP2392-Ab-2;
GM-Tg-mg-MP2392-Ab-1/ GM-Tg-mg-MP2392-Ab-2; GM-Tg-cynog-MP2392-Ab-1/ GM-Tg-cynog-MP2392-Ab-2;
GM-Tg-felg-MP2392-Ab-1/ GM-Tg-felg-MP2392-Ab-2; GM-Tg-cang-MP2392-Ab-1/ GM-Tg-cang-MP2392-Ab-2;
GM-Tg-bovg-MP2392-Ab-1/ GM-Tg-bovg-MP2392-Ab-2; GM-Tg-equg-MP2392-Ab-1/ GM-Tg-equg-MP2392-Ab-2
Products NameAnti-ZGPAT monoclonal antibody
Formatmab
Target NameZGPAT
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ZGPAT benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ZGPAT/ GPATC6/ GPATCH6 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2392
    Target NameZGPAT
    Gene ID84619,229007,296478,719499,100687731,101092923,510866,100060772
    Gene Symbol and Synonyms1500006I01Rik,GPATC6,GPATCH6,KIAA1847,RGD1310801,ZC3H9,ZC3HDC9,ZGPAT,ZIP
    Uniprot AccessionQ8N5A5,Q5PPF5,Q17QX2
    Uniprot Entry NameZGPAT_HUMAN,ZGPAT_RAT,ZGPAT_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000197114
    Target ClassificationN/A

    The target: ZGPAT, gene name: ZGPAT, also named as GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZIP. Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of epidermal growth factor-activated receptor activity and negative regulation of transcription by RNA polymerase II. Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.