Anti-CONA1/ COL23A1 monoclonal antibody

Anti-CONA1/ COL23A1 antibody for FACS & in-vivo assay

Target products collectionGo to COL23A1/COL23A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2395-Ab-1/ GM-Tg-hg-MP2395-Ab-2Anti-Human COL23A1 monoclonal antibodyHuman
GM-Tg-rg-MP2395-Ab-1/ GM-Tg-rg-MP2395-Ab-2Anti-Rat COL23A1 monoclonal antibodyRat
GM-Tg-mg-MP2395-Ab-1/ GM-Tg-mg-MP2395-Ab-2Anti-Mouse COL23A1 monoclonal antibodyMouse
GM-Tg-cynog-MP2395-Ab-1/ GM-Tg-cynog-MP2395-Ab-2Anti-Cynomolgus/ Rhesus macaque COL23A1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2395-Ab-1/ GM-Tg-felg-MP2395-Ab-2Anti-Feline COL23A1 monoclonal antibodyFeline
GM-Tg-cang-MP2395-Ab-1/ GM-Tg-cang-MP2395-Ab-2Anti-Canine COL23A1 monoclonal antibodyCanine
GM-Tg-bovg-MP2395-Ab-1/ GM-Tg-bovg-MP2395-Ab-2Anti-Bovine COL23A1 monoclonal antibodyBovine
GM-Tg-equg-MP2395-Ab-1/ GM-Tg-equg-MP2395-Ab-2Anti-Equine COL23A1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2395-Ab-1/ GM-Tg-hg-MP2395-Ab-2; GM-Tg-rg-MP2395-Ab-1/ GM-Tg-rg-MP2395-Ab-2;
GM-Tg-mg-MP2395-Ab-1/ GM-Tg-mg-MP2395-Ab-2; GM-Tg-cynog-MP2395-Ab-1/ GM-Tg-cynog-MP2395-Ab-2;
GM-Tg-felg-MP2395-Ab-1/ GM-Tg-felg-MP2395-Ab-2; GM-Tg-cang-MP2395-Ab-1/ GM-Tg-cang-MP2395-Ab-2;
GM-Tg-bovg-MP2395-Ab-1/ GM-Tg-bovg-MP2395-Ab-2; GM-Tg-equg-MP2395-Ab-1/ GM-Tg-equg-MP2395-Ab-2
Products NameAnti-COL23A1 monoclonal antibody
Formatmab
Target NameCOL23A1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-COL23A1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CONA1/ COL23A1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2395
    Target NameCOL23A1
    Gene ID91522,237759,353303,709456,607556,101098427,613347,100068381
    Gene Symbol and Synonyms2810458L13Rik,COL23A1
    Uniprot AccessionQ86Y22,Q810Y4
    Uniprot Entry NameCONA1_HUMAN,CONA1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000050767
    Target ClassificationN/A

    The target: COL23A1, gene name: COL23A1, also named as . COL23A1 is a member of the transmembrane collagens, a subfamily of the nonfibrillar collagens that contain a single pass hydrophobic transmembrane domain (Banyard et al., 2003 [PubMed 12644459]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.