Anti-ALKL1/ ALKAL1/ AUGA monoclonal antibody

Anti-ALKL1/ ALKAL1/ AUGA antibody for FACS & in-vivo assay

Target products collectionGo to ALKAL1/ALKAL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2415-Ab-1/ GM-Tg-hg-MP2415-Ab-2Anti-Human ALKAL1 monoclonal antibodyHuman
GM-Tg-rg-MP2415-Ab-1/ GM-Tg-rg-MP2415-Ab-2Anti-Rat ALKAL1 monoclonal antibodyRat
GM-Tg-mg-MP2415-Ab-1/ GM-Tg-mg-MP2415-Ab-2Anti-Mouse ALKAL1 monoclonal antibodyMouse
GM-Tg-cynog-MP2415-Ab-1/ GM-Tg-cynog-MP2415-Ab-2Anti-Cynomolgus/ Rhesus macaque ALKAL1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2415-Ab-1/ GM-Tg-felg-MP2415-Ab-2Anti-Feline ALKAL1 monoclonal antibodyFeline
GM-Tg-cang-MP2415-Ab-1/ GM-Tg-cang-MP2415-Ab-2Anti-Canine ALKAL1 monoclonal antibodyCanine
GM-Tg-bovg-MP2415-Ab-1/ GM-Tg-bovg-MP2415-Ab-2Anti-Bovine ALKAL1 monoclonal antibodyBovine
GM-Tg-equg-MP2415-Ab-1/ GM-Tg-equg-MP2415-Ab-2Anti-Equine ALKAL1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2415-Ab-1/ GM-Tg-hg-MP2415-Ab-2; GM-Tg-rg-MP2415-Ab-1/ GM-Tg-rg-MP2415-Ab-2;
GM-Tg-mg-MP2415-Ab-1/ GM-Tg-mg-MP2415-Ab-2; GM-Tg-cynog-MP2415-Ab-1/ GM-Tg-cynog-MP2415-Ab-2;
GM-Tg-felg-MP2415-Ab-1/ GM-Tg-felg-MP2415-Ab-2; GM-Tg-cang-MP2415-Ab-1/ GM-Tg-cang-MP2415-Ab-2;
GM-Tg-bovg-MP2415-Ab-1/ GM-Tg-bovg-MP2415-Ab-2; GM-Tg-equg-MP2415-Ab-1/ GM-Tg-equg-MP2415-Ab-2
Products NameAnti-ALKAL1 monoclonal antibody
Formatmab
Target NameALKAL1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ALKAL1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ALKL1/ ALKAL1/ AUGA VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2415
    Target NameALKAL1
    Gene ID389658,620393,100910984,717570,608857,101094234,100297122,100050264
    Gene Symbol and SynonymsALKAL1,AUGA,AUGB,Augbeta,EG620393,FAM150A,UNQ9433
    Uniprot AccessionQ6UXT8
    Uniprot Entry NameALKL1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000196711
    Target ClassificationN/A

    The target: ALKAL1, gene name: ALKAL1, also named as AUGA, AUGB, FAM150A, UNQ9433. Enables receptor signaling protein tyrosine kinase activator activity and receptor tyrosine kinase binding activity. Involved in positive regulation of ERK1 and ERK2 cascade; positive regulation of ERK5 cascade; and positive regulation of neuron projection development. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.