Anti-CD5L/ AIM/ API6 monoclonal antibody

Anti-CD5L/ AIM/ API6 antibody for FACS & in-vivo assay

Target products collectionGo to CD5L/CD5L products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2427-Ab-1/ GM-Tg-hg-MP2427-Ab-2Anti-Human CD5L monoclonal antibodyHuman
GM-Tg-rg-MP2427-Ab-1/ GM-Tg-rg-MP2427-Ab-2Anti-Rat CD5L monoclonal antibodyRat
GM-Tg-mg-MP2427-Ab-1/ GM-Tg-mg-MP2427-Ab-2Anti-Mouse CD5L monoclonal antibodyMouse
GM-Tg-cynog-MP2427-Ab-1/ GM-Tg-cynog-MP2427-Ab-2Anti-Cynomolgus/ Rhesus macaque CD5L monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2427-Ab-1/ GM-Tg-felg-MP2427-Ab-2Anti-Feline CD5L monoclonal antibodyFeline
GM-Tg-cang-MP2427-Ab-1/ GM-Tg-cang-MP2427-Ab-2Anti-Canine CD5L monoclonal antibodyCanine
GM-Tg-bovg-MP2427-Ab-1/ GM-Tg-bovg-MP2427-Ab-2Anti-Bovine CD5L monoclonal antibodyBovine
GM-Tg-equg-MP2427-Ab-1/ GM-Tg-equg-MP2427-Ab-2Anti-Equine CD5L monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2427-Ab-1/ GM-Tg-hg-MP2427-Ab-2; GM-Tg-rg-MP2427-Ab-1/ GM-Tg-rg-MP2427-Ab-2;
GM-Tg-mg-MP2427-Ab-1/ GM-Tg-mg-MP2427-Ab-2; GM-Tg-cynog-MP2427-Ab-1/ GM-Tg-cynog-MP2427-Ab-2;
GM-Tg-felg-MP2427-Ab-1/ GM-Tg-felg-MP2427-Ab-2; GM-Tg-cang-MP2427-Ab-1/ GM-Tg-cang-MP2427-Ab-2;
GM-Tg-bovg-MP2427-Ab-1/ GM-Tg-bovg-MP2427-Ab-2; GM-Tg-equg-MP2427-Ab-1/ GM-Tg-equg-MP2427-Ab-2
Products NameAnti-CD5L monoclonal antibody
Formatmab
Target NameCD5L
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CD5L benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CD5L/ AIM/ API6 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2427
    Target NameCD5L
    Gene ID922,11801,310693,718856,609953,101101287,528593,100054450
    Gene Symbol and Synonyms1/6,AAC-11,AIM,API6,CD5L,CT-2,CT2,hAIM,mAIM,Pdp,PRO229,SP-ALPHA,Spalpha
    Uniprot AccessionO43866
    Uniprot Entry NameCD5L_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000073754
    Target ClassificationN/A

    The target: CD5L, gene name: CD5L, also named as AIM, API6, CT-2, PRO229, SP-ALPHA, Spalpha, hAIM. Predicted to enable serine-type endopeptidase activity. Predicted to be involved in zymogen activation. Predicted to act upstream of or within positive regulation of complement-dependent cytotoxicity and regulation of complement activation. Located in cell surface. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.