Anti-IGLC2/ IGLC monoclonal antibody

Anti-IGLC2/ IGLC antibody for FACS & in-vivo assay

Target products collectionGo to IGLC2/IGLC2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2503-Ab-1/ GM-Tg-hg-MP2503-Ab-2Anti-Human IGLC2 monoclonal antibodyHuman
GM-Tg-rg-MP2503-Ab-1/ GM-Tg-rg-MP2503-Ab-2Anti-Rat IGLC2 monoclonal antibodyRat
GM-Tg-mg-MP2503-Ab-1/ GM-Tg-mg-MP2503-Ab-2Anti-Mouse IGLC2 monoclonal antibodyMouse
GM-Tg-cynog-MP2503-Ab-1/ GM-Tg-cynog-MP2503-Ab-2Anti-Cynomolgus/ Rhesus macaque IGLC2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2503-Ab-1/ GM-Tg-felg-MP2503-Ab-2Anti-Feline IGLC2 monoclonal antibodyFeline
GM-Tg-cang-MP2503-Ab-1/ GM-Tg-cang-MP2503-Ab-2Anti-Canine IGLC2 monoclonal antibodyCanine
GM-Tg-bovg-MP2503-Ab-1/ GM-Tg-bovg-MP2503-Ab-2Anti-Bovine IGLC2 monoclonal antibodyBovine
GM-Tg-equg-MP2503-Ab-1/ GM-Tg-equg-MP2503-Ab-2Anti-Equine IGLC2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2503-Ab-1/ GM-Tg-hg-MP2503-Ab-2; GM-Tg-rg-MP2503-Ab-1/ GM-Tg-rg-MP2503-Ab-2;
GM-Tg-mg-MP2503-Ab-1/ GM-Tg-mg-MP2503-Ab-2; GM-Tg-cynog-MP2503-Ab-1/ GM-Tg-cynog-MP2503-Ab-2;
GM-Tg-felg-MP2503-Ab-1/ GM-Tg-felg-MP2503-Ab-2; GM-Tg-cang-MP2503-Ab-1/ GM-Tg-cang-MP2503-Ab-2;
GM-Tg-bovg-MP2503-Ab-1/ GM-Tg-bovg-MP2503-Ab-2; GM-Tg-equg-MP2503-Ab-1/ GM-Tg-equg-MP2503-Ab-2
Products NameAnti-IGLC2 monoclonal antibody
Formatmab
Target NameIGLC2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IGLC2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species IGLC2/ IGLC VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2503
    Target NameIGLC2
    Gene ID3538
    Gene Symbol and SynonymsIGLC,IGLC2
    Uniprot AccessionP0DOY2
    Uniprot Entry NameIGLC2_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000211677
    Target ClassificationN/A

    The target: IGLC2, gene name: IGLC2, also named as IGLC. Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Located in blood microparticle and extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.