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Anti-LAIR2/ CD306 monoclonal antibody
Anti-LAIR2/ CD306 antibody for FACS & in-vivo assay
Go to LAIR2/LAIR2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2547-Ab-1/ GM-Tg-hg-MP2547-Ab-2 | Anti-Human LAIR2 monoclonal antibody | Human |
| GM-Tg-rg-MP2547-Ab-1/ GM-Tg-rg-MP2547-Ab-2 | Anti-Rat LAIR2 monoclonal antibody | Rat |
| GM-Tg-mg-MP2547-Ab-1/ GM-Tg-mg-MP2547-Ab-2 | Anti-Mouse LAIR2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2547-Ab-1/ GM-Tg-cynog-MP2547-Ab-2 | Anti-Cynomolgus/ Rhesus macaque LAIR2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2547-Ab-1/ GM-Tg-felg-MP2547-Ab-2 | Anti-Feline LAIR2 monoclonal antibody | Feline |
| GM-Tg-cang-MP2547-Ab-1/ GM-Tg-cang-MP2547-Ab-2 | Anti-Canine LAIR2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2547-Ab-1/ GM-Tg-bovg-MP2547-Ab-2 | Anti-Bovine LAIR2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2547-Ab-1/ GM-Tg-equg-MP2547-Ab-2 | Anti-Equine LAIR2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2547-Ab-1/ GM-Tg-hg-MP2547-Ab-2; GM-Tg-rg-MP2547-Ab-1/ GM-Tg-rg-MP2547-Ab-2; GM-Tg-mg-MP2547-Ab-1/ GM-Tg-mg-MP2547-Ab-2; GM-Tg-cynog-MP2547-Ab-1/ GM-Tg-cynog-MP2547-Ab-2; GM-Tg-felg-MP2547-Ab-1/ GM-Tg-felg-MP2547-Ab-2; GM-Tg-cang-MP2547-Ab-1/ GM-Tg-cang-MP2547-Ab-2; GM-Tg-bovg-MP2547-Ab-1/ GM-Tg-bovg-MP2547-Ab-2; GM-Tg-equg-MP2547-Ab-1/ GM-Tg-equg-MP2547-Ab-2 |
| Products Name | Anti-LAIR2 monoclonal antibody |
| Format | mab |
| Target Name | LAIR2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-LAIR2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species LAIR2/ CD306 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2547 |
| Target Name | LAIR2 |
| Gene ID | 3904 |
| Gene Symbol and Synonyms | CD306,LAIR2 |
| Uniprot Accession | Q6ISS4 |
| Uniprot Entry Name | LAIR2_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Pregnant state |
| Gene Ensembl | ENSG00000167618 |
| Target Classification | N/A |
The target: LAIR2, gene name: LAIR2, also named as CD306. The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to leukocyte-associated immunoglobulin-like receptor 1, a membrane-bound receptor that modulates innate immune response. The protein encoded by this locus is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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