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Anti-MUC7/ MG2 monoclonal antibody
Anti-MUC7/ MG2 antibody for FACS & in-vivo assay
Go to MUC7/MUC7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2553-Ab-1/ GM-Tg-hg-MP2553-Ab-2 | Anti-Human MUC7 monoclonal antibody | Human |
| GM-Tg-rg-MP2553-Ab-1/ GM-Tg-rg-MP2553-Ab-2 | Anti-Rat MUC7 monoclonal antibody | Rat |
| GM-Tg-mg-MP2553-Ab-1/ GM-Tg-mg-MP2553-Ab-2 | Anti-Mouse MUC7 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2553-Ab-1/ GM-Tg-cynog-MP2553-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MUC7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2553-Ab-1/ GM-Tg-felg-MP2553-Ab-2 | Anti-Feline MUC7 monoclonal antibody | Feline |
| GM-Tg-cang-MP2553-Ab-1/ GM-Tg-cang-MP2553-Ab-2 | Anti-Canine MUC7 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2553-Ab-1/ GM-Tg-bovg-MP2553-Ab-2 | Anti-Bovine MUC7 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2553-Ab-1/ GM-Tg-equg-MP2553-Ab-2 | Anti-Equine MUC7 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2553-Ab-1/ GM-Tg-hg-MP2553-Ab-2; GM-Tg-rg-MP2553-Ab-1/ GM-Tg-rg-MP2553-Ab-2; GM-Tg-mg-MP2553-Ab-1/ GM-Tg-mg-MP2553-Ab-2; GM-Tg-cynog-MP2553-Ab-1/ GM-Tg-cynog-MP2553-Ab-2; GM-Tg-felg-MP2553-Ab-1/ GM-Tg-felg-MP2553-Ab-2; GM-Tg-cang-MP2553-Ab-1/ GM-Tg-cang-MP2553-Ab-2; GM-Tg-bovg-MP2553-Ab-1/ GM-Tg-bovg-MP2553-Ab-2; GM-Tg-equg-MP2553-Ab-1/ GM-Tg-equg-MP2553-Ab-2 |
| Products Name | Anti-MUC7 monoclonal antibody |
| Format | mab |
| Target Name | MUC7 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MUC7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species MUC7/ MG2 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2553 |
| Target Name | MUC7 |
| Gene ID | 4589,17830,707153,102153116,123385155,101905278,102147815 |
| Gene Symbol and Synonyms | MG2,Muc10,MUC7,Prol1 |
| Uniprot Accession | Q8TAX7 |
| Uniprot Entry Name | MUC7_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000171195 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: MUC7, gene name: MUC7, also named as MG2. This gene encodes a small salivary mucin, which is thought to play a role in facilitating the clearance of bacteria in the oral cavity and to aid in mastication, speech, and swallowing. The central domain of this glycoprotein contains tandem repeats, each composed of 23 amino acids. This antimicrobial protein has antibacterial and antifungal activity. The most common allele contains 6 repeats, and some alleles may be associated with susceptibility to asthma. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Oct 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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