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Anti-PA2G5/ PLA2G5/ FRFB monoclonal antibody
Anti-PA2G5/ PLA2G5/ FRFB antibody for FACS & in-vivo assay
Go to PLA2G5/PLA2G5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2560-Ab-1/ GM-Tg-hg-MP2560-Ab-2 | Anti-Human PLA2G5 monoclonal antibody | Human |
| GM-Tg-rg-MP2560-Ab-1/ GM-Tg-rg-MP2560-Ab-2 | Anti-Rat PLA2G5 monoclonal antibody | Rat |
| GM-Tg-mg-MP2560-Ab-1/ GM-Tg-mg-MP2560-Ab-2 | Anti-Mouse PLA2G5 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2560-Ab-1/ GM-Tg-cynog-MP2560-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PLA2G5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2560-Ab-1/ GM-Tg-felg-MP2560-Ab-2 | Anti-Feline PLA2G5 monoclonal antibody | Feline |
| GM-Tg-cang-MP2560-Ab-1/ GM-Tg-cang-MP2560-Ab-2 | Anti-Canine PLA2G5 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2560-Ab-1/ GM-Tg-bovg-MP2560-Ab-2 | Anti-Bovine PLA2G5 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2560-Ab-1/ GM-Tg-equg-MP2560-Ab-2 | Anti-Equine PLA2G5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2560-Ab-1/ GM-Tg-hg-MP2560-Ab-2; GM-Tg-rg-MP2560-Ab-1/ GM-Tg-rg-MP2560-Ab-2; GM-Tg-mg-MP2560-Ab-1/ GM-Tg-mg-MP2560-Ab-2; GM-Tg-cynog-MP2560-Ab-1/ GM-Tg-cynog-MP2560-Ab-2; GM-Tg-felg-MP2560-Ab-1/ GM-Tg-felg-MP2560-Ab-2; GM-Tg-cang-MP2560-Ab-1/ GM-Tg-cang-MP2560-Ab-2; GM-Tg-bovg-MP2560-Ab-1/ GM-Tg-bovg-MP2560-Ab-2; GM-Tg-equg-MP2560-Ab-1/ GM-Tg-equg-MP2560-Ab-2 |
| Products Name | Anti-PLA2G5 monoclonal antibody |
| Format | mab |
| Target Name | PLA2G5 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PLA2G5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species PA2G5/ PLA2G5/ FRFB VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP001831 | human PLA2G5 Lentivirus plasmid |
| ORF Viral Vector | vGMLP001831 | human PLA2G5 Lentivirus particle |
| ORF Viral Vector | pGMLPm000305 | mouse Pla2g5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000305 | mouse Pla2g5 Lentivirus particle |
Target information
| Target ID | GM-MP2560 |
| Target Name | PLA2G5 |
| Gene ID | 5322,29354,704629,101091796,614911,100058536 |
| Gene Symbol and Synonyms | FRFB,GV-PLA2,hVPLA(2),PLA2-10,PLA2G5 |
| Uniprot Accession | P39877,P51433 |
| Uniprot Entry Name | PA2G5_HUMAN,PA2G5_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000127472 |
| Target Classification | N/A |
The target: PLA2G5, gene name: PLA2G5, also named as FRFB, GV-PLA2, PLA2-10, hVPLA(2). This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
