Anti-PSG1/ B1G1/ CD66f monoclonal antibody
Anti-PSG1/ B1G1/ CD66f antibody for FACS & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-MP2563-Ab-1/ GM-Tg-hg-MP2563-Ab-2 | Anti-Human PSG1 monoclonal antibody | Human |
GM-Tg-rg-MP2563-Ab-1/ GM-Tg-rg-MP2563-Ab-2 | Anti-Rat PSG1 monoclonal antibody | Rat |
GM-Tg-mg-MP2563-Ab-1/ GM-Tg-mg-MP2563-Ab-2 | Anti-Mouse PSG1 monoclonal antibody | Mouse |
GM-Tg-cynog-MP2563-Ab-1/ GM-Tg-cynog-MP2563-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PSG1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-MP2563-Ab-1/ GM-Tg-felg-MP2563-Ab-2 | Anti-Feline PSG1 monoclonal antibody | Feline |
GM-Tg-cang-MP2563-Ab-1/ GM-Tg-cang-MP2563-Ab-2 | Anti-Canine PSG1 monoclonal antibody | Canine |
GM-Tg-bovg-MP2563-Ab-1/ GM-Tg-bovg-MP2563-Ab-2 | Anti-Bovine PSG1 monoclonal antibody | Bovine |
GM-Tg-equg-MP2563-Ab-1/ GM-Tg-equg-MP2563-Ab-2 | Anti-Equine PSG1 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-MP2563-Ab-1/ GM-Tg-hg-MP2563-Ab-2; GM-Tg-rg-MP2563-Ab-1/ GM-Tg-rg-MP2563-Ab-2; GM-Tg-mg-MP2563-Ab-1/ GM-Tg-mg-MP2563-Ab-2; GM-Tg-cynog-MP2563-Ab-1/ GM-Tg-cynog-MP2563-Ab-2; GM-Tg-felg-MP2563-Ab-1/ GM-Tg-felg-MP2563-Ab-2; GM-Tg-cang-MP2563-Ab-1/ GM-Tg-cang-MP2563-Ab-2; GM-Tg-bovg-MP2563-Ab-1/ GM-Tg-bovg-MP2563-Ab-2; GM-Tg-equg-MP2563-Ab-1/ GM-Tg-equg-MP2563-Ab-2 |
Products Name | Anti-PSG1 monoclonal antibody |
Format | mab |
Target Name | PSG1 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-PSG1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species PSG1/ B1G1/ CD66f VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | pGMLP003213 | human PSG1 Lentivirus plasmid |
ORF Viral Vector | vGMLP003213 | human PSG1 Lentivirus particle |
Target information
Target ID | GM-MP2563 |
Target Name | PSG1 |
Gene ID | 5669 |
Gene Symbol and Synonyms | B1G1,CD66f,DHFRP2,FL-NCA-1/2,PBG1,PS-beta-C/D,PS-beta-G-1,PSBG-1,PSBG1,PSG1,PSG95,PSGGA,PSGIIA,SP1 |
Uniprot Accession | P11464 |
Uniprot Entry Name | PSG1_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000231924 |
Target Classification | N/A |
The target: PSG1, gene name: PSG1, also named as B1G1, CD66f, DHFRP2, FL-NCA-1/2, PBG1, PS-beta-C/D, PS-beta-G-1, PSBG-1, PSBG1, PSG95, PSGGA, PSGIIA, SP1. The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).[supplied by OMIM, Oct 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.