Anti-PSG1/ B1G1/ CD66f monoclonal antibody

Anti-PSG1/ B1G1/ CD66f antibody for FACS & in-vivo assay

Target products collectionGo to PSG1/PSG1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2563-Ab-1/ GM-Tg-hg-MP2563-Ab-2Anti-Human PSG1 monoclonal antibodyHuman
GM-Tg-rg-MP2563-Ab-1/ GM-Tg-rg-MP2563-Ab-2Anti-Rat PSG1 monoclonal antibodyRat
GM-Tg-mg-MP2563-Ab-1/ GM-Tg-mg-MP2563-Ab-2Anti-Mouse PSG1 monoclonal antibodyMouse
GM-Tg-cynog-MP2563-Ab-1/ GM-Tg-cynog-MP2563-Ab-2Anti-Cynomolgus/ Rhesus macaque PSG1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2563-Ab-1/ GM-Tg-felg-MP2563-Ab-2Anti-Feline PSG1 monoclonal antibodyFeline
GM-Tg-cang-MP2563-Ab-1/ GM-Tg-cang-MP2563-Ab-2Anti-Canine PSG1 monoclonal antibodyCanine
GM-Tg-bovg-MP2563-Ab-1/ GM-Tg-bovg-MP2563-Ab-2Anti-Bovine PSG1 monoclonal antibodyBovine
GM-Tg-equg-MP2563-Ab-1/ GM-Tg-equg-MP2563-Ab-2Anti-Equine PSG1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2563-Ab-1/ GM-Tg-hg-MP2563-Ab-2; GM-Tg-rg-MP2563-Ab-1/ GM-Tg-rg-MP2563-Ab-2;
GM-Tg-mg-MP2563-Ab-1/ GM-Tg-mg-MP2563-Ab-2; GM-Tg-cynog-MP2563-Ab-1/ GM-Tg-cynog-MP2563-Ab-2;
GM-Tg-felg-MP2563-Ab-1/ GM-Tg-felg-MP2563-Ab-2; GM-Tg-cang-MP2563-Ab-1/ GM-Tg-cang-MP2563-Ab-2;
GM-Tg-bovg-MP2563-Ab-1/ GM-Tg-bovg-MP2563-Ab-2; GM-Tg-equg-MP2563-Ab-1/ GM-Tg-equg-MP2563-Ab-2
Products NameAnti-PSG1 monoclonal antibody
Formatmab
Target NamePSG1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PSG1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PSG1/ B1G1/ CD66f VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP003213human PSG1 Lentivirus plasmid
    ORF Viral VectorvGMLP003213human PSG1 Lentivirus particle


    Target information

    Target IDGM-MP2563
    Target NamePSG1
    Gene ID5669
    Gene Symbol and SynonymsB1G1,CD66f,DHFRP2,FL-NCA-1/2,PBG1,PS-beta-C/D,PS-beta-G-1,PSBG-1,PSBG1,PSG1,PSG95,PSGGA,PSGIIA,SP1
    Uniprot AccessionP11464
    Uniprot Entry NamePSG1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000231924
    Target ClassificationN/A

    The target: PSG1, gene name: PSG1, also named as B1G1, CD66f, DHFRP2, FL-NCA-1/2, PBG1, PS-beta-C/D, PS-beta-G-1, PSBG-1, PSBG1, PSG95, PSGGA, PSGIIA, SP1. The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).[supplied by OMIM, Oct 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.