Anti-PSG7/ PSBG-7/ PSG1 monoclonal antibody
Anti-PSG7/ PSBG-7/ PSG1 antibody for FACS & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-MP2566-Ab-1/ GM-Tg-hg-MP2566-Ab-2 | Anti-Human PSG7 monoclonal antibody | Human |
GM-Tg-rg-MP2566-Ab-1/ GM-Tg-rg-MP2566-Ab-2 | Anti-Rat PSG7 monoclonal antibody | Rat |
GM-Tg-mg-MP2566-Ab-1/ GM-Tg-mg-MP2566-Ab-2 | Anti-Mouse PSG7 monoclonal antibody | Mouse |
GM-Tg-cynog-MP2566-Ab-1/ GM-Tg-cynog-MP2566-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PSG7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-MP2566-Ab-1/ GM-Tg-felg-MP2566-Ab-2 | Anti-Feline PSG7 monoclonal antibody | Feline |
GM-Tg-cang-MP2566-Ab-1/ GM-Tg-cang-MP2566-Ab-2 | Anti-Canine PSG7 monoclonal antibody | Canine |
GM-Tg-bovg-MP2566-Ab-1/ GM-Tg-bovg-MP2566-Ab-2 | Anti-Bovine PSG7 monoclonal antibody | Bovine |
GM-Tg-equg-MP2566-Ab-1/ GM-Tg-equg-MP2566-Ab-2 | Anti-Equine PSG7 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-MP2566-Ab-1/ GM-Tg-hg-MP2566-Ab-2; GM-Tg-rg-MP2566-Ab-1/ GM-Tg-rg-MP2566-Ab-2; GM-Tg-mg-MP2566-Ab-1/ GM-Tg-mg-MP2566-Ab-2; GM-Tg-cynog-MP2566-Ab-1/ GM-Tg-cynog-MP2566-Ab-2; GM-Tg-felg-MP2566-Ab-1/ GM-Tg-felg-MP2566-Ab-2; GM-Tg-cang-MP2566-Ab-1/ GM-Tg-cang-MP2566-Ab-2; GM-Tg-bovg-MP2566-Ab-1/ GM-Tg-bovg-MP2566-Ab-2; GM-Tg-equg-MP2566-Ab-1/ GM-Tg-equg-MP2566-Ab-2 |
Products Name | Anti-PSG7 monoclonal antibody |
Format | mab |
Target Name | PSG7 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-PSG7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species PSG7/ PSBG-7/ PSG1 VLP (virus-like particle) (Products Developing) |
Target information
Target ID | GM-MP2566 |
Target Name | PSG7 |
Gene ID | 5676 |
Gene Symbol and Synonyms | PS-beta-G-7,PSBG-7,PSG1,PSG7,PSGGA |
Uniprot Accession | Q13046 |
Uniprot Entry Name | PSG7_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000221878 |
Target Classification | N/A |
The target: PSG7, gene name: PSG7, also named as PSBG-7, PSG1, PSGGA. This gene is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.