Anti-PSG8/ PSG1 monoclonal antibody

Anti-PSG8/ PSG1 antibody for FACS & in-vivo assay

Target products collectionGo to PSG8/PSG8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2567-Ab-1/ GM-Tg-hg-MP2567-Ab-2Anti-Human PSG8 monoclonal antibodyHuman
GM-Tg-rg-MP2567-Ab-1/ GM-Tg-rg-MP2567-Ab-2Anti-Rat PSG8 monoclonal antibodyRat
GM-Tg-mg-MP2567-Ab-1/ GM-Tg-mg-MP2567-Ab-2Anti-Mouse PSG8 monoclonal antibodyMouse
GM-Tg-cynog-MP2567-Ab-1/ GM-Tg-cynog-MP2567-Ab-2Anti-Cynomolgus/ Rhesus macaque PSG8 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2567-Ab-1/ GM-Tg-felg-MP2567-Ab-2Anti-Feline PSG8 monoclonal antibodyFeline
GM-Tg-cang-MP2567-Ab-1/ GM-Tg-cang-MP2567-Ab-2Anti-Canine PSG8 monoclonal antibodyCanine
GM-Tg-bovg-MP2567-Ab-1/ GM-Tg-bovg-MP2567-Ab-2Anti-Bovine PSG8 monoclonal antibodyBovine
GM-Tg-equg-MP2567-Ab-1/ GM-Tg-equg-MP2567-Ab-2Anti-Equine PSG8 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2567-Ab-1/ GM-Tg-hg-MP2567-Ab-2; GM-Tg-rg-MP2567-Ab-1/ GM-Tg-rg-MP2567-Ab-2;
GM-Tg-mg-MP2567-Ab-1/ GM-Tg-mg-MP2567-Ab-2; GM-Tg-cynog-MP2567-Ab-1/ GM-Tg-cynog-MP2567-Ab-2;
GM-Tg-felg-MP2567-Ab-1/ GM-Tg-felg-MP2567-Ab-2; GM-Tg-cang-MP2567-Ab-1/ GM-Tg-cang-MP2567-Ab-2;
GM-Tg-bovg-MP2567-Ab-1/ GM-Tg-bovg-MP2567-Ab-2; GM-Tg-equg-MP2567-Ab-1/ GM-Tg-equg-MP2567-Ab-2
Products NameAnti-PSG8 monoclonal antibody
Formatmab
Target NamePSG8
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PSG8 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PSG8/ PSG1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2567
    Target NamePSG8
    Gene ID440533
    Gene Symbol and SynonymsPSG1,PSG8
    Uniprot AccessionQ9UQ74
    Uniprot Entry NamePSG8_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000124467
    Target ClassificationN/A

    The target: PSG8, gene name: PSG8, also named as PSG1. The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.