Anti-SIRPD/ PTPNS1L2/ dJ576H24.4 monoclonal antibody

Anti-SIRPD/ PTPNS1L2/ dJ576H24.4 antibody for FACS & in-vivo assay

Target products collectionGo to SIRPD/SIRPD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2570-Ab-1/ GM-Tg-hg-MP2570-Ab-2Anti-Human SIRPD monoclonal antibodyHuman
GM-Tg-rg-MP2570-Ab-1/ GM-Tg-rg-MP2570-Ab-2Anti-Rat SIRPD monoclonal antibodyRat
GM-Tg-mg-MP2570-Ab-1/ GM-Tg-mg-MP2570-Ab-2Anti-Mouse SIRPD monoclonal antibodyMouse
GM-Tg-cynog-MP2570-Ab-1/ GM-Tg-cynog-MP2570-Ab-2Anti-Cynomolgus/ Rhesus macaque SIRPD monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2570-Ab-1/ GM-Tg-felg-MP2570-Ab-2Anti-Feline SIRPD monoclonal antibodyFeline
GM-Tg-cang-MP2570-Ab-1/ GM-Tg-cang-MP2570-Ab-2Anti-Canine SIRPD monoclonal antibodyCanine
GM-Tg-bovg-MP2570-Ab-1/ GM-Tg-bovg-MP2570-Ab-2Anti-Bovine SIRPD monoclonal antibodyBovine
GM-Tg-equg-MP2570-Ab-1/ GM-Tg-equg-MP2570-Ab-2Anti-Equine SIRPD monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2570-Ab-1/ GM-Tg-hg-MP2570-Ab-2; GM-Tg-rg-MP2570-Ab-1/ GM-Tg-rg-MP2570-Ab-2;
GM-Tg-mg-MP2570-Ab-1/ GM-Tg-mg-MP2570-Ab-2; GM-Tg-cynog-MP2570-Ab-1/ GM-Tg-cynog-MP2570-Ab-2;
GM-Tg-felg-MP2570-Ab-1/ GM-Tg-felg-MP2570-Ab-2; GM-Tg-cang-MP2570-Ab-1/ GM-Tg-cang-MP2570-Ab-2;
GM-Tg-bovg-MP2570-Ab-1/ GM-Tg-bovg-MP2570-Ab-2; GM-Tg-equg-MP2570-Ab-1/ GM-Tg-equg-MP2570-Ab-2
Products NameAnti-SIRPD monoclonal antibody
Formatmab
Target NameSIRPD
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SIRPD benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SIRPD/ PTPNS1L2/ dJ576H24.4 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2570
    Target NameSIRPD
    Gene ID128646
    Gene Symbol and SynonymsdJ576H24.4,PTPNS1L2,SIRPD
    Uniprot AccessionQ9H106
    Uniprot Entry NameSIRPD_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000125900
    Target ClassificationN/A

    The target: SIRPD, gene name: SIRPD, also named as PTPNS1L2, dJ576H24.4. Predicted to be located in extracellular region. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.