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Anti-WNT3A monoclonal antibody
Anti-WNT3A antibody for FACS & in-vivo assay
Go to WNT3A/WNT3A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2573-Ab-1/ GM-Tg-hg-MP2573-Ab-2 | Anti-Human WNT3A monoclonal antibody | Human |
| GM-Tg-rg-MP2573-Ab-1/ GM-Tg-rg-MP2573-Ab-2 | Anti-Rat WNT3A monoclonal antibody | Rat |
| GM-Tg-mg-MP2573-Ab-1/ GM-Tg-mg-MP2573-Ab-2 | Anti-Mouse WNT3A monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2573-Ab-1/ GM-Tg-cynog-MP2573-Ab-2 | Anti-Cynomolgus/ Rhesus macaque WNT3A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2573-Ab-1/ GM-Tg-felg-MP2573-Ab-2 | Anti-Feline WNT3A monoclonal antibody | Feline |
| GM-Tg-cang-MP2573-Ab-1/ GM-Tg-cang-MP2573-Ab-2 | Anti-Canine WNT3A monoclonal antibody | Canine |
| GM-Tg-bovg-MP2573-Ab-1/ GM-Tg-bovg-MP2573-Ab-2 | Anti-Bovine WNT3A monoclonal antibody | Bovine |
| GM-Tg-equg-MP2573-Ab-1/ GM-Tg-equg-MP2573-Ab-2 | Anti-Equine WNT3A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2573-Ab-1/ GM-Tg-hg-MP2573-Ab-2; GM-Tg-rg-MP2573-Ab-1/ GM-Tg-rg-MP2573-Ab-2; GM-Tg-mg-MP2573-Ab-1/ GM-Tg-mg-MP2573-Ab-2; GM-Tg-cynog-MP2573-Ab-1/ GM-Tg-cynog-MP2573-Ab-2; GM-Tg-felg-MP2573-Ab-1/ GM-Tg-felg-MP2573-Ab-2; GM-Tg-cang-MP2573-Ab-1/ GM-Tg-cang-MP2573-Ab-2; GM-Tg-bovg-MP2573-Ab-1/ GM-Tg-bovg-MP2573-Ab-2; GM-Tg-equg-MP2573-Ab-1/ GM-Tg-equg-MP2573-Ab-2 |
| Products Name | Anti-WNT3A monoclonal antibody |
| Format | mab |
| Target Name | WNT3A |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-WNT3A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species WNT3A VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-MP2573-Ag-1 | wingless-type MMTV integration site family, member 3A (WNT3A) protein |
| ORF Viral Vector | pGMLP002017 | human WNT3A Lentivirus plasmid |
| ORF Viral Vector | vGMLP002017 | human WNT3A Lentivirus particle |
| ORF Viral Vector | pGMLV000404 | rat Wnt3a Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001965 | mouse Wnt3a Lentivirus plasmid |
| ORF Viral Vector | vGMLV000404 | rat Wnt3a Lentivirus particle |
| ORF Viral Vector | vGMLPm001965 | mouse Wnt3a Lentivirus particle |
Target information
| Target ID | GM-MP2573 |
| Target Name | WNT3A |
| Gene ID | 89780,22416,303181,696200,482208,101080607,522467,100061145 |
| Gene Symbol and Synonyms | vt,Wnt-3a,WNT3A |
| Uniprot Accession | P56704 |
| Uniprot Entry Name | WNT3A_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Cytokine Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000154342 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: WNT3A, gene name: WNT3A, also named as . The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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