Anti-KI3X1/ KIR3DX1/ KIR3DL0 monoclonal antibody

Anti-KI3X1/ KIR3DX1/ KIR3DL0 antibody for FACS & in-vivo assay

Target products collectionGo to KIR3DX1/KIR3DX1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2581-Ab-1/ GM-Tg-hg-MP2581-Ab-2Anti-Human KIR3DX1 monoclonal antibodyHuman
GM-Tg-rg-MP2581-Ab-1/ GM-Tg-rg-MP2581-Ab-2Anti-Rat KIR3DX1 monoclonal antibodyRat
GM-Tg-mg-MP2581-Ab-1/ GM-Tg-mg-MP2581-Ab-2Anti-Mouse KIR3DX1 monoclonal antibodyMouse
GM-Tg-cynog-MP2581-Ab-1/ GM-Tg-cynog-MP2581-Ab-2Anti-Cynomolgus/ Rhesus macaque KIR3DX1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2581-Ab-1/ GM-Tg-felg-MP2581-Ab-2Anti-Feline KIR3DX1 monoclonal antibodyFeline
GM-Tg-cang-MP2581-Ab-1/ GM-Tg-cang-MP2581-Ab-2Anti-Canine KIR3DX1 monoclonal antibodyCanine
GM-Tg-bovg-MP2581-Ab-1/ GM-Tg-bovg-MP2581-Ab-2Anti-Bovine KIR3DX1 monoclonal antibodyBovine
GM-Tg-equg-MP2581-Ab-1/ GM-Tg-equg-MP2581-Ab-2Anti-Equine KIR3DX1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2581-Ab-1/ GM-Tg-hg-MP2581-Ab-2; GM-Tg-rg-MP2581-Ab-1/ GM-Tg-rg-MP2581-Ab-2;
GM-Tg-mg-MP2581-Ab-1/ GM-Tg-mg-MP2581-Ab-2; GM-Tg-cynog-MP2581-Ab-1/ GM-Tg-cynog-MP2581-Ab-2;
GM-Tg-felg-MP2581-Ab-1/ GM-Tg-felg-MP2581-Ab-2; GM-Tg-cang-MP2581-Ab-1/ GM-Tg-cang-MP2581-Ab-2;
GM-Tg-bovg-MP2581-Ab-1/ GM-Tg-bovg-MP2581-Ab-2; GM-Tg-equg-MP2581-Ab-1/ GM-Tg-equg-MP2581-Ab-2
Products NameAnti-KIR3DX1 monoclonal antibody
Formatmab
Target NameKIR3DX1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-KIR3DX1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species KI3X1/ KIR3DX1/ KIR3DL0 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2581
    Target NameKIR3DX1
    Gene ID90011
    Gene Symbol and SynonymsKIR3DL0,KIR3DX1,LENG12
    Uniprot AccessionQ9H7L2
    Uniprot Entry NameKI3X1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000104970
    Target ClassificationN/A

    The target: KIR3DX1, gene name: KIR3DX1, also named as KIR3DL0, LENG12. Predicted to be located in extracellular region. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.