Anti-TULP1/ LCA15/ RP14 monoclonal antibody

Anti-TULP1/ LCA15/ RP14 antibody for FACS & in-vivo assay

Target products collectionGo to TULP1/TULP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2584-Ab-1/ GM-Tg-hg-MP2584-Ab-2Anti-Human TULP1 monoclonal antibodyHuman
GM-Tg-rg-MP2584-Ab-1/ GM-Tg-rg-MP2584-Ab-2Anti-Rat TULP1 monoclonal antibodyRat
GM-Tg-mg-MP2584-Ab-1/ GM-Tg-mg-MP2584-Ab-2Anti-Mouse TULP1 monoclonal antibodyMouse
GM-Tg-cynog-MP2584-Ab-1/ GM-Tg-cynog-MP2584-Ab-2Anti-Cynomolgus/ Rhesus macaque TULP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2584-Ab-1/ GM-Tg-felg-MP2584-Ab-2Anti-Feline TULP1 monoclonal antibodyFeline
GM-Tg-cang-MP2584-Ab-1/ GM-Tg-cang-MP2584-Ab-2Anti-Canine TULP1 monoclonal antibodyCanine
GM-Tg-bovg-MP2584-Ab-1/ GM-Tg-bovg-MP2584-Ab-2Anti-Bovine TULP1 monoclonal antibodyBovine
GM-Tg-equg-MP2584-Ab-1/ GM-Tg-equg-MP2584-Ab-2Anti-Equine TULP1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2584-Ab-1/ GM-Tg-hg-MP2584-Ab-2; GM-Tg-rg-MP2584-Ab-1/ GM-Tg-rg-MP2584-Ab-2;
GM-Tg-mg-MP2584-Ab-1/ GM-Tg-mg-MP2584-Ab-2; GM-Tg-cynog-MP2584-Ab-1/ GM-Tg-cynog-MP2584-Ab-2;
GM-Tg-felg-MP2584-Ab-1/ GM-Tg-felg-MP2584-Ab-2; GM-Tg-cang-MP2584-Ab-1/ GM-Tg-cang-MP2584-Ab-2;
GM-Tg-bovg-MP2584-Ab-1/ GM-Tg-bovg-MP2584-Ab-2; GM-Tg-equg-MP2584-Ab-1/ GM-Tg-equg-MP2584-Ab-2
Products NameAnti-TULP1 monoclonal antibody
Formatmab
Target NameTULP1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TULP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TULP1/ LCA15/ RP14 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2584
    Target NameTULP1
    Gene ID7287,22157,309900,718796,481758,101099126,613862,100053500
    Gene Symbol and SynonymsLCA15,RP14,TUBL1,TULP1,Tulp1l
    Uniprot AccessionO00294
    Uniprot Entry NameTULP1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000112041
    Target ClassificationN/A

    The target: TULP1, gene name: TULP1, also named as LCA15, RP14, TUBL1. This gene encodes a member of the tubby-like gene family (TULPs). Members of this family have been identified in plants, vertebrates, and invertebrates. TULP proteins share a conserved C-terminal region of approximately 200 amino acid residues. The protein encoded by this gene is thought to play a role in the physiology of photoreceptors. Mutations in this gene are associated with recessive juvenile retinitis pigmentosa and Leber congenital amaurosis-15. [provided by RefSeq, Nov 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.