Anti-PXDNL/ PMR1/ PRM1 monoclonal antibody

Anti-PXDNL/ PMR1/ PRM1 antibody for FACS & in-vivo assay

Target products collectionGo to PXDNL/PXDNL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2592-Ab-1/ GM-Tg-hg-MP2592-Ab-2Anti-Human PXDNL monoclonal antibodyHuman
GM-Tg-rg-MP2592-Ab-1/ GM-Tg-rg-MP2592-Ab-2Anti-Rat PXDNL monoclonal antibodyRat
GM-Tg-mg-MP2592-Ab-1/ GM-Tg-mg-MP2592-Ab-2Anti-Mouse PXDNL monoclonal antibodyMouse
GM-Tg-cynog-MP2592-Ab-1/ GM-Tg-cynog-MP2592-Ab-2Anti-Cynomolgus/ Rhesus macaque PXDNL monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2592-Ab-1/ GM-Tg-felg-MP2592-Ab-2Anti-Feline PXDNL monoclonal antibodyFeline
GM-Tg-cang-MP2592-Ab-1/ GM-Tg-cang-MP2592-Ab-2Anti-Canine PXDNL monoclonal antibodyCanine
GM-Tg-bovg-MP2592-Ab-1/ GM-Tg-bovg-MP2592-Ab-2Anti-Bovine PXDNL monoclonal antibodyBovine
GM-Tg-equg-MP2592-Ab-1/ GM-Tg-equg-MP2592-Ab-2Anti-Equine PXDNL monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2592-Ab-1/ GM-Tg-hg-MP2592-Ab-2; GM-Tg-rg-MP2592-Ab-1/ GM-Tg-rg-MP2592-Ab-2;
GM-Tg-mg-MP2592-Ab-1/ GM-Tg-mg-MP2592-Ab-2; GM-Tg-cynog-MP2592-Ab-1/ GM-Tg-cynog-MP2592-Ab-2;
GM-Tg-felg-MP2592-Ab-1/ GM-Tg-felg-MP2592-Ab-2; GM-Tg-cang-MP2592-Ab-1/ GM-Tg-cang-MP2592-Ab-2;
GM-Tg-bovg-MP2592-Ab-1/ GM-Tg-bovg-MP2592-Ab-2; GM-Tg-equg-MP2592-Ab-1/ GM-Tg-equg-MP2592-Ab-2
Products NameAnti-PXDNL monoclonal antibody
Formatmab
Target NamePXDNL
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PXDNL benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PXDNL/ PMR1/ PRM1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2592
    Target NamePXDNL
    Gene ID137902,717095,486944,101093491,100053180
    Gene Symbol and SynonymsPMR1,PRM1,PXDNL,VPO2
    Uniprot AccessionA1KZ92
    Uniprot Entry NamePXDNL_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000147485
    Target ClassificationN/A

    The target: PXDNL, gene name: PXDNL, also named as PMR1, PRM1, VPO2. Predicted to enable heme binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.