Anti-CABP1/ CALBRAIN/ HCALB_BR monoclonal antibody

Anti-CABP1/ CALBRAIN/ HCALB_BR antibody for FACS & in-vivo assay

Target products collectionGo to CABP1/CABP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2594-Ab-1/ GM-Tg-hg-MP2594-Ab-2Anti-Human CABP1 monoclonal antibodyHuman
GM-Tg-rg-MP2594-Ab-1/ GM-Tg-rg-MP2594-Ab-2Anti-Rat CABP1 monoclonal antibodyRat
GM-Tg-mg-MP2594-Ab-1/ GM-Tg-mg-MP2594-Ab-2Anti-Mouse CABP1 monoclonal antibodyMouse
GM-Tg-cynog-MP2594-Ab-1/ GM-Tg-cynog-MP2594-Ab-2Anti-Cynomolgus/ Rhesus macaque CABP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2594-Ab-1/ GM-Tg-felg-MP2594-Ab-2Anti-Feline CABP1 monoclonal antibodyFeline
GM-Tg-cang-MP2594-Ab-1/ GM-Tg-cang-MP2594-Ab-2Anti-Canine CABP1 monoclonal antibodyCanine
GM-Tg-bovg-MP2594-Ab-1/ GM-Tg-bovg-MP2594-Ab-2Anti-Bovine CABP1 monoclonal antibodyBovine
GM-Tg-equg-MP2594-Ab-1/ GM-Tg-equg-MP2594-Ab-2Anti-Equine CABP1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2594-Ab-1/ GM-Tg-hg-MP2594-Ab-2; GM-Tg-rg-MP2594-Ab-1/ GM-Tg-rg-MP2594-Ab-2;
GM-Tg-mg-MP2594-Ab-1/ GM-Tg-mg-MP2594-Ab-2; GM-Tg-cynog-MP2594-Ab-1/ GM-Tg-cynog-MP2594-Ab-2;
GM-Tg-felg-MP2594-Ab-1/ GM-Tg-felg-MP2594-Ab-2; GM-Tg-cang-MP2594-Ab-1/ GM-Tg-cang-MP2594-Ab-2;
GM-Tg-bovg-MP2594-Ab-1/ GM-Tg-bovg-MP2594-Ab-2; GM-Tg-equg-MP2594-Ab-1/ GM-Tg-equg-MP2594-Ab-2
Products NameAnti-CABP1 monoclonal antibody
Formatmab
Target NameCABP1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CABP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CABP1/ CALBRAIN/ HCALB_BR VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2594
    Target NameCABP1
    Gene ID9478,29867,171051,697825,477516,101082189,281653,100050122
    Gene Symbol and SynonymsCABP1,CALBRAIN,caldendrin,HCALB_BR
    Uniprot AccessionQ9NZU7,O88751,Q9N1R0
    Uniprot Entry NameCABP1_HUMAN,CABP1_RAT,CABP1_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000157782
    Target ClassificationN/A

    The target: CABP1, gene name: CABP1, also named as CALBRAIN, HCALB_BR. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. This gene encodes a protein that belongs to a subfamily of calcium binding proteins which share similarity to calmodulin. The protein encoded by this gene regulates the gating of voltage-gated calcium ion channels. This protein inhibits calcium-dependent inactivation and supports calcium-dependent facilitation of ion channels containing voltage-dependent L-type calcium channel subunit alpha-1C. This protein also regulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors, P/Q-type voltage-gated calcium channels, and transient receptor potential channel TRPC5. This gene is predominantly expressed in retina and brain. Alternative splicing results in multiple transcript variants encoding disinct isoforms. [provided by RefSeq, Jul 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.