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Anti-TUB/ RDOB/ rd5 monoclonal antibody
Anti-TUB/ RDOB/ rd5 antibody for FACS & in-vivo assay
Go to TUB/TUB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2597-Ab-1/ GM-Tg-hg-MP2597-Ab-2 | Anti-Human TUB monoclonal antibody | Human |
| GM-Tg-rg-MP2597-Ab-1/ GM-Tg-rg-MP2597-Ab-2 | Anti-Rat TUB monoclonal antibody | Rat |
| GM-Tg-mg-MP2597-Ab-1/ GM-Tg-mg-MP2597-Ab-2 | Anti-Mouse TUB monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2597-Ab-1/ GM-Tg-cynog-MP2597-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TUB monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2597-Ab-1/ GM-Tg-felg-MP2597-Ab-2 | Anti-Feline TUB monoclonal antibody | Feline |
| GM-Tg-cang-MP2597-Ab-1/ GM-Tg-cang-MP2597-Ab-2 | Anti-Canine TUB monoclonal antibody | Canine |
| GM-Tg-bovg-MP2597-Ab-1/ GM-Tg-bovg-MP2597-Ab-2 | Anti-Bovine TUB monoclonal antibody | Bovine |
| GM-Tg-equg-MP2597-Ab-1/ GM-Tg-equg-MP2597-Ab-2 | Anti-Equine TUB monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2597-Ab-1/ GM-Tg-hg-MP2597-Ab-2; GM-Tg-rg-MP2597-Ab-1/ GM-Tg-rg-MP2597-Ab-2; GM-Tg-mg-MP2597-Ab-1/ GM-Tg-mg-MP2597-Ab-2; GM-Tg-cynog-MP2597-Ab-1/ GM-Tg-cynog-MP2597-Ab-2; GM-Tg-felg-MP2597-Ab-1/ GM-Tg-felg-MP2597-Ab-2; GM-Tg-cang-MP2597-Ab-1/ GM-Tg-cang-MP2597-Ab-2; GM-Tg-bovg-MP2597-Ab-1/ GM-Tg-bovg-MP2597-Ab-2; GM-Tg-equg-MP2597-Ab-1/ GM-Tg-equg-MP2597-Ab-2 |
| Products Name | Anti-TUB monoclonal antibody |
| Format | mab |
| Target Name | TUB |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-TUB benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species TUB/ RDOB/ rd5 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP001593 | human TUB Lentivirus particle |
| ORF Viral Vector | pGMLP001593 | human TUB Lentivirus plasmid |
Target information
| Target ID | GM-MP2597 |
| Target Name | TUB |
| Gene ID | 7275,22141,25609,706054,485377,101089894,539051,100070898 |
| Gene Symbol and Synonyms | rd5,RDOB,TUB |
| Uniprot Accession | P50607,O88808 |
| Uniprot Entry Name | TUB_HUMAN,TUB_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000166402 |
| Target Classification | N/A |
The target: TUB, gene name: TUB, also named as RDOB, rd5. This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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