Anti-SNTB2/ D16S2531E/ EST25263 monoclonal antibody

Anti-SNTB2/ D16S2531E/ EST25263 antibody for FACS & in-vivo assay

Target products collectionGo to SNTB2/SNTB2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2598-Ab-1/ GM-Tg-hg-MP2598-Ab-2Anti-Human SNTB2 monoclonal antibodyHuman
GM-Tg-rg-MP2598-Ab-1/ GM-Tg-rg-MP2598-Ab-2Anti-Rat SNTB2 monoclonal antibodyRat
GM-Tg-mg-MP2598-Ab-1/ GM-Tg-mg-MP2598-Ab-2Anti-Mouse SNTB2 monoclonal antibodyMouse
GM-Tg-cynog-MP2598-Ab-1/ GM-Tg-cynog-MP2598-Ab-2Anti-Cynomolgus/ Rhesus macaque SNTB2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2598-Ab-1/ GM-Tg-felg-MP2598-Ab-2Anti-Feline SNTB2 monoclonal antibodyFeline
GM-Tg-cang-MP2598-Ab-1/ GM-Tg-cang-MP2598-Ab-2Anti-Canine SNTB2 monoclonal antibodyCanine
GM-Tg-bovg-MP2598-Ab-1/ GM-Tg-bovg-MP2598-Ab-2Anti-Bovine SNTB2 monoclonal antibodyBovine
GM-Tg-equg-MP2598-Ab-1/ GM-Tg-equg-MP2598-Ab-2Anti-Equine SNTB2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2598-Ab-1/ GM-Tg-hg-MP2598-Ab-2; GM-Tg-rg-MP2598-Ab-1/ GM-Tg-rg-MP2598-Ab-2;
GM-Tg-mg-MP2598-Ab-1/ GM-Tg-mg-MP2598-Ab-2; GM-Tg-cynog-MP2598-Ab-1/ GM-Tg-cynog-MP2598-Ab-2;
GM-Tg-felg-MP2598-Ab-1/ GM-Tg-felg-MP2598-Ab-2; GM-Tg-cang-MP2598-Ab-1/ GM-Tg-cang-MP2598-Ab-2;
GM-Tg-bovg-MP2598-Ab-1/ GM-Tg-bovg-MP2598-Ab-2; GM-Tg-equg-MP2598-Ab-1/ GM-Tg-equg-MP2598-Ab-2
Products NameAnti-SNTB2 monoclonal antibody
Formatmab
Target NameSNTB2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SNTB2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SNTB2/ D16S2531E/ EST25263 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm005337mouse Sntb2 Lentivirus plasmid
    ORF Viral VectorvGMLPm005337mouse Sntb2 Lentivirus particle


    Target information

    Target IDGM-MP2598
    Target NameSNTB2
    Gene ID6645,20650,689421,704333,479675,101082361,786534,100066988
    Gene Symbol and SynonymsD16S2531E,EST25263,Snt2,SNT2B2,SNT3,SNTB2,SNTL
    Uniprot AccessionQ13425
    Uniprot Entry NameSNTB2_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000168807
    Target ClassificationN/A

    The target: SNTB2, gene name: SNTB2, also named as D16S2531E, EST25263, SNT2B2, SNT3, SNTL. Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.