Anti-PRS42/ PRSS42/ TESSP2 monoclonal antibody

Anti-PRS42/ PRSS42/ TESSP2 antibody for FACS & in-vivo assay

Target products collectionGo to PRSS42/PRSS42 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2601-Ab-1/ GM-Tg-hg-MP2601-Ab-2Anti-Human PRSS42 monoclonal antibodyHuman
GM-Tg-rg-MP2601-Ab-1/ GM-Tg-rg-MP2601-Ab-2Anti-Rat PRSS42 monoclonal antibodyRat
GM-Tg-mg-MP2601-Ab-1/ GM-Tg-mg-MP2601-Ab-2Anti-Mouse PRSS42 monoclonal antibodyMouse
GM-Tg-cynog-MP2601-Ab-1/ GM-Tg-cynog-MP2601-Ab-2Anti-Cynomolgus/ Rhesus macaque PRSS42 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2601-Ab-1/ GM-Tg-felg-MP2601-Ab-2Anti-Feline PRSS42 monoclonal antibodyFeline
GM-Tg-cang-MP2601-Ab-1/ GM-Tg-cang-MP2601-Ab-2Anti-Canine PRSS42 monoclonal antibodyCanine
GM-Tg-bovg-MP2601-Ab-1/ GM-Tg-bovg-MP2601-Ab-2Anti-Bovine PRSS42 monoclonal antibodyBovine
GM-Tg-equg-MP2601-Ab-1/ GM-Tg-equg-MP2601-Ab-2Anti-Equine PRSS42 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2601-Ab-1/ GM-Tg-hg-MP2601-Ab-2; GM-Tg-rg-MP2601-Ab-1/ GM-Tg-rg-MP2601-Ab-2;
GM-Tg-mg-MP2601-Ab-1/ GM-Tg-mg-MP2601-Ab-2; GM-Tg-cynog-MP2601-Ab-1/ GM-Tg-cynog-MP2601-Ab-2;
GM-Tg-felg-MP2601-Ab-1/ GM-Tg-felg-MP2601-Ab-2; GM-Tg-cang-MP2601-Ab-1/ GM-Tg-cang-MP2601-Ab-2;
GM-Tg-bovg-MP2601-Ab-1/ GM-Tg-bovg-MP2601-Ab-2; GM-Tg-equg-MP2601-Ab-1/ GM-Tg-equg-MP2601-Ab-2
Products NameAnti-PRSS42 monoclonal antibody
Formatmab
Target NamePRSS42
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PRSS42 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PRS42/ PRSS42/ TESSP2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2601
    Target NamePRSS42
    Gene ID339906,504538
    Gene Symbol and SynonymsPRSS42,PRSS42P,TESSP2
    Uniprot AccessionQ7Z5A4
    Uniprot Entry NamePRS42_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000178055
    Target ClassificationN/A

    The target: PRSS42, gene name: PRSS42, also named as TESSP2. This gene encodes a member of a cluster of testis-specific serine proteases. The orthologous mouse gene is expressed during meiosis in pachytene spermatocytes and is required for germ cell survival. This human locus is represented as a pseudogene because it contains an early stop codon that disrupts the trypsin domain, compared to the mouse ortholog. [provided by RefSeq, Jan 2019].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.