Anti-CFA65/ CFAP65/ CCDC108 monoclonal antibody

Anti-CFA65/ CFAP65/ CCDC108 antibody for FACS & in-vivo assay

Target products collectionGo to CFAP65/CFAP65 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2602-Ab-1/ GM-Tg-hg-MP2602-Ab-2Anti-Human CFAP65 monoclonal antibodyHuman
GM-Tg-rg-MP2602-Ab-1/ GM-Tg-rg-MP2602-Ab-2Anti-Rat CFAP65 monoclonal antibodyRat
GM-Tg-mg-MP2602-Ab-1/ GM-Tg-mg-MP2602-Ab-2Anti-Mouse CFAP65 monoclonal antibodyMouse
GM-Tg-cynog-MP2602-Ab-1/ GM-Tg-cynog-MP2602-Ab-2Anti-Cynomolgus/ Rhesus macaque CFAP65 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2602-Ab-1/ GM-Tg-felg-MP2602-Ab-2Anti-Feline CFAP65 monoclonal antibodyFeline
GM-Tg-cang-MP2602-Ab-1/ GM-Tg-cang-MP2602-Ab-2Anti-Canine CFAP65 monoclonal antibodyCanine
GM-Tg-bovg-MP2602-Ab-1/ GM-Tg-bovg-MP2602-Ab-2Anti-Bovine CFAP65 monoclonal antibodyBovine
GM-Tg-equg-MP2602-Ab-1/ GM-Tg-equg-MP2602-Ab-2Anti-Equine CFAP65 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2602-Ab-1/ GM-Tg-hg-MP2602-Ab-2; GM-Tg-rg-MP2602-Ab-1/ GM-Tg-rg-MP2602-Ab-2;
GM-Tg-mg-MP2602-Ab-1/ GM-Tg-mg-MP2602-Ab-2; GM-Tg-cynog-MP2602-Ab-1/ GM-Tg-cynog-MP2602-Ab-2;
GM-Tg-felg-MP2602-Ab-1/ GM-Tg-felg-MP2602-Ab-2; GM-Tg-cang-MP2602-Ab-1/ GM-Tg-cang-MP2602-Ab-2;
GM-Tg-bovg-MP2602-Ab-1/ GM-Tg-bovg-MP2602-Ab-2; GM-Tg-equg-MP2602-Ab-1/ GM-Tg-equg-MP2602-Ab-2
Products NameAnti-CFAP65 monoclonal antibody
Formatmab
Target NameCFAP65
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CFAP65 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CFA65/ CFAP65/ CCDC108 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2602
    Target NameCFAP65
    Gene ID255101,241116,301521,701296,488532,101099894,107131175,100058974
    Gene Symbol and SynonymsA230051F10,B230363K08Rik,CCDC108,CFAP65,SPGF40
    Uniprot AccessionQ6ZU64
    Uniprot Entry NameCFA65_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000181378
    Target ClassificationN/A

    The target: CFAP65, gene name: CFAP65, also named as CCDC108. The protein encoded by this gene has putative coiled-coil domains and may be a transmembrane protein. The chicken ortholog of this gene is involved in the Rose-comb mutation, which is a large chromosome inversion, resulting in altered comb morphology and defects in sperm motility. [provided by RefSeq, Aug 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.