Anti-PRS55/ PRSS55/ CT153 monoclonal antibody

Anti-PRS55/ PRSS55/ CT153 antibody for FACS & in-vivo assay

Target products collectionGo to PRSS55/PRSS55 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2603-Ab-1/ GM-Tg-hg-MP2603-Ab-2Anti-Human PRSS55 monoclonal antibodyHuman
GM-Tg-rg-MP2603-Ab-1/ GM-Tg-rg-MP2603-Ab-2Anti-Rat PRSS55 monoclonal antibodyRat
GM-Tg-mg-MP2603-Ab-1/ GM-Tg-mg-MP2603-Ab-2Anti-Mouse PRSS55 monoclonal antibodyMouse
GM-Tg-cynog-MP2603-Ab-1/ GM-Tg-cynog-MP2603-Ab-2Anti-Cynomolgus/ Rhesus macaque PRSS55 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2603-Ab-1/ GM-Tg-felg-MP2603-Ab-2Anti-Feline PRSS55 monoclonal antibodyFeline
GM-Tg-cang-MP2603-Ab-1/ GM-Tg-cang-MP2603-Ab-2Anti-Canine PRSS55 monoclonal antibodyCanine
GM-Tg-bovg-MP2603-Ab-1/ GM-Tg-bovg-MP2603-Ab-2Anti-Bovine PRSS55 monoclonal antibodyBovine
GM-Tg-equg-MP2603-Ab-1/ GM-Tg-equg-MP2603-Ab-2Anti-Equine PRSS55 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2603-Ab-1/ GM-Tg-hg-MP2603-Ab-2; GM-Tg-rg-MP2603-Ab-1/ GM-Tg-rg-MP2603-Ab-2;
GM-Tg-mg-MP2603-Ab-1/ GM-Tg-mg-MP2603-Ab-2; GM-Tg-cynog-MP2603-Ab-1/ GM-Tg-cynog-MP2603-Ab-2;
GM-Tg-felg-MP2603-Ab-1/ GM-Tg-felg-MP2603-Ab-2; GM-Tg-cang-MP2603-Ab-1/ GM-Tg-cang-MP2603-Ab-2;
GM-Tg-bovg-MP2603-Ab-1/ GM-Tg-bovg-MP2603-Ab-2; GM-Tg-equg-MP2603-Ab-1/ GM-Tg-equg-MP2603-Ab-2
Products NameAnti-PRSS55 monoclonal antibody
Formatmab
Target NamePRSS55
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PRSS55 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PRS55/ PRSS55/ CT153 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2603
    Target NamePRSS55
    Gene ID203074,71037,683415,698379,521059,100061967
    Gene Symbol and Synonyms4933401F05Rik,CT153,PRSS55,T-SP1,TSP1,UNQ9391
    Uniprot AccessionQ6UWB4
    Uniprot Entry NamePRS55_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000184647
    Target ClassificationN/A

    The target: PRSS55, gene name: PRSS55, also named as CT153, T-SP1, TSP1, UNQ9391. This gene encodes a member of a group of membrane-anchored chymotrypsin (S1)-like serine proteases. The enocoded protein is primarily expressed in the Leydig and Sertoli cells of the testis and may be involved in male fertility. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.