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Anti-SRCA/ SRL/ SAR monoclonal antibody
Anti-SRCA/ SRL/ SAR antibody for FACS & in-vivo assay
Go to SRL/SRL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2604-Ab-1/ GM-Tg-hg-MP2604-Ab-2 | Anti-Human SRL monoclonal antibody | Human |
| GM-Tg-rg-MP2604-Ab-1/ GM-Tg-rg-MP2604-Ab-2 | Anti-Rat SRL monoclonal antibody | Rat |
| GM-Tg-mg-MP2604-Ab-1/ GM-Tg-mg-MP2604-Ab-2 | Anti-Mouse SRL monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2604-Ab-1/ GM-Tg-cynog-MP2604-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SRL monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2604-Ab-1/ GM-Tg-felg-MP2604-Ab-2 | Anti-Feline SRL monoclonal antibody | Feline |
| GM-Tg-cang-MP2604-Ab-1/ GM-Tg-cang-MP2604-Ab-2 | Anti-Canine SRL monoclonal antibody | Canine |
| GM-Tg-bovg-MP2604-Ab-1/ GM-Tg-bovg-MP2604-Ab-2 | Anti-Bovine SRL monoclonal antibody | Bovine |
| GM-Tg-equg-MP2604-Ab-1/ GM-Tg-equg-MP2604-Ab-2 | Anti-Equine SRL monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2604-Ab-1/ GM-Tg-hg-MP2604-Ab-2; GM-Tg-rg-MP2604-Ab-1/ GM-Tg-rg-MP2604-Ab-2; GM-Tg-mg-MP2604-Ab-1/ GM-Tg-mg-MP2604-Ab-2; GM-Tg-cynog-MP2604-Ab-1/ GM-Tg-cynog-MP2604-Ab-2; GM-Tg-felg-MP2604-Ab-1/ GM-Tg-felg-MP2604-Ab-2; GM-Tg-cang-MP2604-Ab-1/ GM-Tg-cang-MP2604-Ab-2; GM-Tg-bovg-MP2604-Ab-1/ GM-Tg-bovg-MP2604-Ab-2; GM-Tg-equg-MP2604-Ab-1/ GM-Tg-equg-MP2604-Ab-2 |
| Products Name | Anti-SRL monoclonal antibody |
| Format | mab |
| Target Name | SRL |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SRL benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species SRCA/ SRL/ SAR VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP001800 | human SRL Lentivirus particle |
| ORF Viral Vector | pGMLP001800 | human SRL Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004094 | mouse Srl Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004094 | mouse Srl Lentivirus particle |
Target information
| Target ID | GM-MP2604 |
| Target Name | SRL |
| Gene ID | 6345,106393,302948,704655,101095708,513912,100069703 |
| Gene Symbol and Synonyms | 9830004M20Rik,SAR,SRL |
| Uniprot Accession | Q86TD4 |
| Uniprot Entry Name | SRCA_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000185739 |
| Target Classification | N/A |
The target: SRL, gene name: SRL, also named as SAR. Predicted to enable GTP binding activity. Predicted to be involved in endocytosis and endosomal transport. Predicted to act upstream of or within response to muscle activity involved in regulation of muscle adaptation and store-operated calcium entry. Predicted to be located in sarcoplasmic reticulum lumen and sarcoplasmic reticulum membrane. Predicted to be active in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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