Anti-MUC19/ MUC-19 monoclonal antibody

Anti-MUC19/ MUC-19 antibody for FACS & in-vivo assay

Target products collectionGo to MUC19/MUC19 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2606-Ab-1/ GM-Tg-hg-MP2606-Ab-2Anti-Human MUC19 monoclonal antibodyHuman
GM-Tg-rg-MP2606-Ab-1/ GM-Tg-rg-MP2606-Ab-2Anti-Rat MUC19 monoclonal antibodyRat
GM-Tg-mg-MP2606-Ab-1/ GM-Tg-mg-MP2606-Ab-2Anti-Mouse MUC19 monoclonal antibodyMouse
GM-Tg-cynog-MP2606-Ab-1/ GM-Tg-cynog-MP2606-Ab-2Anti-Cynomolgus/ Rhesus macaque MUC19 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2606-Ab-1/ GM-Tg-felg-MP2606-Ab-2Anti-Feline MUC19 monoclonal antibodyFeline
GM-Tg-cang-MP2606-Ab-1/ GM-Tg-cang-MP2606-Ab-2Anti-Canine MUC19 monoclonal antibodyCanine
GM-Tg-bovg-MP2606-Ab-1/ GM-Tg-bovg-MP2606-Ab-2Anti-Bovine MUC19 monoclonal antibodyBovine
GM-Tg-equg-MP2606-Ab-1/ GM-Tg-equg-MP2606-Ab-2Anti-Equine MUC19 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2606-Ab-1/ GM-Tg-hg-MP2606-Ab-2; GM-Tg-rg-MP2606-Ab-1/ GM-Tg-rg-MP2606-Ab-2;
GM-Tg-mg-MP2606-Ab-1/ GM-Tg-mg-MP2606-Ab-2; GM-Tg-cynog-MP2606-Ab-1/ GM-Tg-cynog-MP2606-Ab-2;
GM-Tg-felg-MP2606-Ab-1/ GM-Tg-felg-MP2606-Ab-2; GM-Tg-cang-MP2606-Ab-1/ GM-Tg-cang-MP2606-Ab-2;
GM-Tg-bovg-MP2606-Ab-1/ GM-Tg-bovg-MP2606-Ab-2; GM-Tg-equg-MP2606-Ab-1/ GM-Tg-equg-MP2606-Ab-2
Products NameAnti-MUC19 monoclonal antibody
Formatmab
Target NameMUC19
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MUC19 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MUC19/ MUC-19 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2606
    Target NameMUC19
    Gene ID283463,239611,497227,698572,102156424,101097566,100140959,100053372
    Gene Symbol and SynonymsBSM,BSM1,MUC-19,MUC19,Muc19l1,RGD1624205,sld,SMGC
    Uniprot AccessionQ7Z5P9,P98091
    Uniprot Entry NameMUC19_HUMAN,MUC19_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000205592
    Target ClassificationN/A

    The target: MUC19, gene name: MUC19, also named as MUC-19. This gene encodes a member of the gel-forming mucin protein family. Mucin family members are glycoproteins that have tandem repeats which are extensively O-glycosylated. The structural features of mucin proteins are responsible for the gel-like properties of mucus. The encoded protein may be involved in disruption of the ocular surface in Sjogren syndrome. [provided by RefSeq, Apr 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.