Anti-IGHV8-51-1/ IGHVIII-51-1/ 3-51.1P monoclonal antibody

Anti-IGHV8-51-1/ IGHVIII-51-1/ 3-51.1P antibody for FACS & in-vivo assay

Target products collectionGo to IGHV8-51-1/IGHVIII-51-1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2608-Ab-1/ GM-Tg-hg-MP2608-Ab-2Anti-Human IGHV8-51-1/IGHVIII-51-1 monoclonal antibodyHuman
GM-Tg-rg-MP2608-Ab-1/ GM-Tg-rg-MP2608-Ab-2Anti-Rat IGHV8-51-1/IGHVIII-51-1 monoclonal antibodyRat
GM-Tg-mg-MP2608-Ab-1/ GM-Tg-mg-MP2608-Ab-2Anti-Mouse IGHV8-51-1/IGHVIII-51-1 monoclonal antibodyMouse
GM-Tg-cynog-MP2608-Ab-1/ GM-Tg-cynog-MP2608-Ab-2Anti-Cynomolgus/ Rhesus macaque IGHV8-51-1/IGHVIII-51-1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2608-Ab-1/ GM-Tg-felg-MP2608-Ab-2Anti-Feline IGHV8-51-1/IGHVIII-51-1 monoclonal antibodyFeline
GM-Tg-cang-MP2608-Ab-1/ GM-Tg-cang-MP2608-Ab-2Anti-Canine IGHV8-51-1/IGHVIII-51-1 monoclonal antibodyCanine
GM-Tg-bovg-MP2608-Ab-1/ GM-Tg-bovg-MP2608-Ab-2Anti-Bovine IGHV8-51-1/IGHVIII-51-1 monoclonal antibodyBovine
GM-Tg-equg-MP2608-Ab-1/ GM-Tg-equg-MP2608-Ab-2Anti-Equine IGHV8-51-1/IGHVIII-51-1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2608-Ab-1/ GM-Tg-hg-MP2608-Ab-2; GM-Tg-rg-MP2608-Ab-1/ GM-Tg-rg-MP2608-Ab-2;
GM-Tg-mg-MP2608-Ab-1/ GM-Tg-mg-MP2608-Ab-2; GM-Tg-cynog-MP2608-Ab-1/ GM-Tg-cynog-MP2608-Ab-2;
GM-Tg-felg-MP2608-Ab-1/ GM-Tg-felg-MP2608-Ab-2; GM-Tg-cang-MP2608-Ab-1/ GM-Tg-cang-MP2608-Ab-2;
GM-Tg-bovg-MP2608-Ab-1/ GM-Tg-bovg-MP2608-Ab-2; GM-Tg-equg-MP2608-Ab-1/ GM-Tg-equg-MP2608-Ab-2
Products NameAnti-IGHV8-51-1/IGHVIII-51-1 monoclonal antibody
Formatmab
Target NameIGHV8-51-1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IGHV8-51-1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species IGHV8-51-1/ IGHVIII-51-1/ 3-51.1P VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2608
    Target NameIGHV8-51-1
    Gene ID28343
    Gene Symbol and Synonyms3-51.1P,IGHV8-51-1,IGHVIII-51-1,IGHVIII511
    Uniprot AccessionN/A
    Uniprot Entry Name
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000254167
    Target ClassificationN/A

    The target: IGHV8-51-1, gene name: IGHVIII-51-1, also named as 3-51.1P, IGHVIII511. Predicted to be involved in adaptive immune response. Predicted to be located in extracellular region and plasma membrane. Predicted to be part of immunoglobulin complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.