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Anti-CREG1/ CREG functional antibody
Anti-CREG1/ CREG functional antibody for cell culture, ELISA & in-vivo assay
Go to CREG1/CREG1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0122-Ab-1/ GM-Tg-hg-SE0122-Ab-2 | Anti-Human CREG1 monoclonal antibody | Human |
| GM-Tg-rg-SE0122-Ab-1/ GM-Tg-rg-SE0122-Ab-2 | Anti-Rat CREG1 monoclonal antibody | Rat |
| GM-Tg-mg-SE0122-Ab-1/ GM-Tg-mg-SE0122-Ab-2 | Anti-Mouse CREG1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0122-Ab-1/ GM-Tg-cynog-SE0122-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CREG1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0122-Ab-1/ GM-Tg-felg-SE0122-Ab-2 | Anti-Feline CREG1 monoclonal antibody | Feline |
| GM-Tg-cang-SE0122-Ab-1/ GM-Tg-cang-SE0122-Ab-2 | Anti-Canine CREG1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0122-Ab-1/ GM-Tg-bovg-SE0122-Ab-2 | Anti-Bovine CREG1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0122-Ab-1/ GM-Tg-equg-SE0122-Ab-2 | Anti-Equine CREG1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0122-Ab-1/ GM-Tg-hg-SE0122-Ab-2; GM-Tg-rg-SE0122-Ab-1/ GM-Tg-rg-SE0122-Ab-2; GM-Tg-mg-SE0122-Ab-1/ GM-Tg-mg-SE0122-Ab-2; GM-Tg-cynog-SE0122-Ab-1/ GM-Tg-cynog-SE0122-Ab-2; GM-Tg-felg-SE0122-Ab-1/ GM-Tg-felg-SE0122-Ab-2; GM-Tg-cang-SE0122-Ab-1/ GM-Tg-cang-SE0122-Ab-2; GM-Tg-bovg-SE0122-Ab-1/ GM-Tg-bovg-SE0122-Ab-2; GM-Tg-equg-SE0122-Ab-1/ GM-Tg-equg-SE0122-Ab-2 |
| Products Name | Anti-CREG1 monoclonal antibody |
| Format | mab |
| Target Name | CREG1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CREG1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0122-Ag-1 | Recombinant multi-species CREG1/ CREG protein |
| ORF Viral Vector | vGMLP004358 | human CREG1 Lentivirus particle |
| ORF Viral Vector | pGMLP004358 | human CREG1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004134 | mouse Creg1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004134 | mouse Creg1 Lentivirus particle |
Target information
| Target ID | GM-SE0122 |
| Target Name | CREG1 |
| Gene ID | 8804,433375,289185,701021,100686738,101098599,530908,100056817 |
| Gene Symbol and Synonyms | CREG,CREG1 |
| Uniprot Accession | O75629 |
| Uniprot Entry Name | CREG1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000143162 |
| Target Classification | N/A |
The target: CREG1, gene name: CREG1, also named as CREG. The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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