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Anti-TAFA4/ FAM19A4/ TAFA-4 functional antibody
Anti-TAFA4/ FAM19A4/ TAFA-4 functional antibody for cell culture, ELISA & in-vivo assay
Go to FAM19A4/FAM19A4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0196-Ab-1/ GM-Tg-hg-SE0196-Ab-2 | Anti-Human FAM19A4 monoclonal antibody | Human |
| GM-Tg-rg-SE0196-Ab-1/ GM-Tg-rg-SE0196-Ab-2 | Anti-Rat FAM19A4 monoclonal antibody | Rat |
| GM-Tg-mg-SE0196-Ab-1/ GM-Tg-mg-SE0196-Ab-2 | Anti-Mouse FAM19A4 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0196-Ab-1/ GM-Tg-cynog-SE0196-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FAM19A4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0196-Ab-1/ GM-Tg-felg-SE0196-Ab-2 | Anti-Feline FAM19A4 monoclonal antibody | Feline |
| GM-Tg-cang-SE0196-Ab-1/ GM-Tg-cang-SE0196-Ab-2 | Anti-Canine FAM19A4 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0196-Ab-1/ GM-Tg-bovg-SE0196-Ab-2 | Anti-Bovine FAM19A4 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0196-Ab-1/ GM-Tg-equg-SE0196-Ab-2 | Anti-Equine FAM19A4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0196-Ab-1/ GM-Tg-hg-SE0196-Ab-2; GM-Tg-rg-SE0196-Ab-1/ GM-Tg-rg-SE0196-Ab-2; GM-Tg-mg-SE0196-Ab-1/ GM-Tg-mg-SE0196-Ab-2; GM-Tg-cynog-SE0196-Ab-1/ GM-Tg-cynog-SE0196-Ab-2; GM-Tg-felg-SE0196-Ab-1/ GM-Tg-felg-SE0196-Ab-2; GM-Tg-cang-SE0196-Ab-1/ GM-Tg-cang-SE0196-Ab-2; GM-Tg-bovg-SE0196-Ab-1/ GM-Tg-bovg-SE0196-Ab-2; GM-Tg-equg-SE0196-Ab-1/ GM-Tg-equg-SE0196-Ab-2 |
| Products Name | Anti-FAM19A4 monoclonal antibody |
| Format | mab |
| Target Name | FAM19A4 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FAM19A4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0196-Ag-1 | Recombinant multi-species TAFA4/ FAM19A4/ TAFA-4 protein |
| Cytokine | GM-Tg-g-SE0196-Ag-1 | family with sequence similarity 19 (chemokine (C-C motif)-like), member A4 (FAM19A4) protein |
| ORF Viral Vector | pGMLP004273 | human FAM19A4 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004273 | human FAM19A4 Lentivirus particle |
| ORF Viral Vector | pGMLPm003323 | mouse Fam19a4 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003323 | mouse Fam19a4 Lentivirus particle |
Target information
| Target ID | GM-SE0196 |
| Target Name | FAM19A4 |
| Gene ID | 151647,320701,689043,696987,610997,101089425,616873,100629222 |
| Gene Symbol and Synonyms | C130034I18Rik,FAM19A4,Fam19a4 Tafa-4,TAFA-4,TAFA4 |
| Uniprot Accession | Q96LR4 |
| Uniprot Entry Name | TAFA4_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000163377 |
| Target Classification | N/A |
The target: FAM19A4, gene name: FAM19A4, also named as TAFA-4, TAFA4. This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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