- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-GDF9/ POF14 functional antibody
Anti-GDF9/ POF14 functional antibody for cell culture, ELISA & in-vivo assay
Go to GDF9/GDF9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0241-Ab-1/ GM-Tg-hg-SE0241-Ab-2 | Anti-Human GDF9 monoclonal antibody | Human |
| GM-Tg-rg-SE0241-Ab-1/ GM-Tg-rg-SE0241-Ab-2 | Anti-Rat GDF9 monoclonal antibody | Rat |
| GM-Tg-mg-SE0241-Ab-1/ GM-Tg-mg-SE0241-Ab-2 | Anti-Mouse GDF9 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0241-Ab-1/ GM-Tg-cynog-SE0241-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GDF9 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0241-Ab-1/ GM-Tg-felg-SE0241-Ab-2 | Anti-Feline GDF9 monoclonal antibody | Feline |
| GM-Tg-cang-SE0241-Ab-1/ GM-Tg-cang-SE0241-Ab-2 | Anti-Canine GDF9 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0241-Ab-1/ GM-Tg-bovg-SE0241-Ab-2 | Anti-Bovine GDF9 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0241-Ab-1/ GM-Tg-equg-SE0241-Ab-2 | Anti-Equine GDF9 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0241-Ab-1/ GM-Tg-hg-SE0241-Ab-2; GM-Tg-rg-SE0241-Ab-1/ GM-Tg-rg-SE0241-Ab-2; GM-Tg-mg-SE0241-Ab-1/ GM-Tg-mg-SE0241-Ab-2; GM-Tg-cynog-SE0241-Ab-1/ GM-Tg-cynog-SE0241-Ab-2; GM-Tg-felg-SE0241-Ab-1/ GM-Tg-felg-SE0241-Ab-2; GM-Tg-cang-SE0241-Ab-1/ GM-Tg-cang-SE0241-Ab-2; GM-Tg-bovg-SE0241-Ab-1/ GM-Tg-bovg-SE0241-Ab-2; GM-Tg-equg-SE0241-Ab-1/ GM-Tg-equg-SE0241-Ab-2 |
| Products Name | Anti-GDF9 monoclonal antibody |
| Format | mab |
| Target Name | GDF9 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-GDF9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0241-Ag-1 | Recombinant multi-species GDF9/ POF14 protein |
| Cytokine | GM-Tg-g-SE0241-Ag-1 | growth differentiation factor 9 (GDF9) protein |
| ORF Viral Vector | vGMLP003024 | human GDF9 Lentivirus particle |
| ORF Viral Vector | pGMLP003024 | human GDF9 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002543 | mouse Gdf9 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002543 | mouse Gdf9 Lentivirus particle |
Target information
| Target ID | GM-SE0241 |
| Target Name | GDF9 |
| Gene ID | 2661,14566,59304,712792,100313495,100306942,282574,100072822 |
| Gene Symbol and Synonyms | Gdf-9,GDF9,POF14 |
| Uniprot Accession | O60383,Q9GK68 |
| Uniprot Entry Name | GDF9_HUMAN,GDF9_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000164404 |
| Target Classification | N/A |
The target: GDF9, gene name: GDF9, also named as POF14. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates ovarian function. Reduced expression of this gene may be associated with polycystic ovary syndrome and mutations in this gene may be more common in mothers of dizygotic twins. [provided by RefSeq, Jul 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
