Anti-LYZL1/ KAAG648/ LYC2 functional antibody

Anti-LYZL1/ KAAG648/ LYC2 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to LYZL1/LYZL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0332-Ab-1/ GM-Tg-hg-SE0332-Ab-2Anti-Human LYZL1 monoclonal antibodyHuman
GM-Tg-rg-SE0332-Ab-1/ GM-Tg-rg-SE0332-Ab-2Anti-Rat LYZL1 monoclonal antibodyRat
GM-Tg-mg-SE0332-Ab-1/ GM-Tg-mg-SE0332-Ab-2Anti-Mouse LYZL1 monoclonal antibodyMouse
GM-Tg-cynog-SE0332-Ab-1/ GM-Tg-cynog-SE0332-Ab-2Anti-Cynomolgus/ Rhesus macaque LYZL1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0332-Ab-1/ GM-Tg-felg-SE0332-Ab-2Anti-Feline LYZL1 monoclonal antibodyFeline
GM-Tg-cang-SE0332-Ab-1/ GM-Tg-cang-SE0332-Ab-2Anti-Canine LYZL1 monoclonal antibodyCanine
GM-Tg-bovg-SE0332-Ab-1/ GM-Tg-bovg-SE0332-Ab-2Anti-Bovine LYZL1 monoclonal antibodyBovine
GM-Tg-equg-SE0332-Ab-1/ GM-Tg-equg-SE0332-Ab-2Anti-Equine LYZL1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0332-Ab-1/ GM-Tg-hg-SE0332-Ab-2; GM-Tg-rg-SE0332-Ab-1/ GM-Tg-rg-SE0332-Ab-2;
GM-Tg-mg-SE0332-Ab-1/ GM-Tg-mg-SE0332-Ab-2; GM-Tg-cynog-SE0332-Ab-1/ GM-Tg-cynog-SE0332-Ab-2;
GM-Tg-felg-SE0332-Ab-1/ GM-Tg-felg-SE0332-Ab-2; GM-Tg-cang-SE0332-Ab-1/ GM-Tg-cang-SE0332-Ab-2;
GM-Tg-bovg-SE0332-Ab-1/ GM-Tg-bovg-SE0332-Ab-2; GM-Tg-equg-SE0332-Ab-1/ GM-Tg-equg-SE0332-Ab-2
Products NameAnti-LYZL1 monoclonal antibody
Formatmab
Target NameLYZL1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-LYZL1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0332-Ag-1Recombinant multi-species LYZL1/ KAAG648/ LYC2 protein
    ORF Viral VectorpGMLP003980human LYZL1 Lentivirus plasmid
    ORF Viral VectorvGMLP003980human LYZL1 Lentivirus particle


    Target information

    Target IDGM-SE0332
    Target NameLYZL1
    Gene ID84569,100055156
    Gene Symbol and SynonymsbA534G20.1,KAAG648,LYC2,LYZD1,LYZL1,PRO1278
    Uniprot AccessionQ6UWQ5
    Uniprot Entry NameLYZL1_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000120563
    Target ClassificationN/A

    The target: LYZL1, gene name: LYZL1, also named as KAAG648, LYC2, LYZD1, PRO1278, bA534G20.1. Predicted to enable lysozyme activity. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.