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Anti-PA2G4/ EBP1/ HG4-1 functional antibody
Anti-PA2G4/ EBP1/ HG4-1 functional antibody for cell culture, ELISA & in-vivo assay
Go to PA2G4/PA2G4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0394-Ab-1/ GM-Tg-hg-SE0394-Ab-2 | Anti-Human PA2G4 monoclonal antibody | Human |
| GM-Tg-rg-SE0394-Ab-1/ GM-Tg-rg-SE0394-Ab-2 | Anti-Rat PA2G4 monoclonal antibody | Rat |
| GM-Tg-mg-SE0394-Ab-1/ GM-Tg-mg-SE0394-Ab-2 | Anti-Mouse PA2G4 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0394-Ab-1/ GM-Tg-cynog-SE0394-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PA2G4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0394-Ab-1/ GM-Tg-felg-SE0394-Ab-2 | Anti-Feline PA2G4 monoclonal antibody | Feline |
| GM-Tg-cang-SE0394-Ab-1/ GM-Tg-cang-SE0394-Ab-2 | Anti-Canine PA2G4 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0394-Ab-1/ GM-Tg-bovg-SE0394-Ab-2 | Anti-Bovine PA2G4 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0394-Ab-1/ GM-Tg-equg-SE0394-Ab-2 | Anti-Equine PA2G4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0394-Ab-1/ GM-Tg-hg-SE0394-Ab-2; GM-Tg-rg-SE0394-Ab-1/ GM-Tg-rg-SE0394-Ab-2; GM-Tg-mg-SE0394-Ab-1/ GM-Tg-mg-SE0394-Ab-2; GM-Tg-cynog-SE0394-Ab-1/ GM-Tg-cynog-SE0394-Ab-2; GM-Tg-felg-SE0394-Ab-1/ GM-Tg-felg-SE0394-Ab-2; GM-Tg-cang-SE0394-Ab-1/ GM-Tg-cang-SE0394-Ab-2; GM-Tg-bovg-SE0394-Ab-1/ GM-Tg-bovg-SE0394-Ab-2; GM-Tg-equg-SE0394-Ab-1/ GM-Tg-equg-SE0394-Ab-2 |
| Products Name | Anti-PA2G4 monoclonal antibody |
| Format | mab |
| Target Name | PA2G4 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PA2G4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0394-Ag-1 | Recombinant multi-species PA2G4/ EBP1/ HG4-1 protein |
| ORF Viral Vector | pGMLP000102 | human PA2G4 Lentivirus plasmid |
| ORF Viral Vector | vGMLP000102 | human PA2G4 Lentivirus particle |
| ORF Viral Vector | pGMLPm001425 | mouse Pa2g4 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001425 | mouse Pa2g4 Lentivirus particle |
Target information
| Target ID | GM-SE0394 |
| Target Name | PA2G4 |
| Gene ID | 5036,18813,288778,107000890,474396,101095110,540272 |
| Gene Symbol and Synonyms | 38kDa,EBP1,HG4-1,ITAF45,p38-2G4,PA2G4,Plfap |
| Uniprot Accession | Q9UQ80,Q6AYD3 |
| Uniprot Entry Name | PA2G4_HUMAN,PA2G4_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000170515 |
| Target Classification | N/A |
The target: PA2G4, gene name: PA2G4, also named as EBP1, HG4-1, p38-2G4. This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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